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Thyroid Adenoma with Extensive Extracellular Mucin Deposition: Report of a Case

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Abstract

A thyroid tumor with extensive extracellular mucin deposition is extremely rare. We herein describe a case of a thyroid adenoma with prominent myxoid stroma. A 63-year-old man presented with a mass in his right anterior neck. Radiological examinations showed this mass to be a thyroid tumor with a cystic component. The histopathological findings showed the stroma of this tumor to consist of abundant myxoid materials which stained gray-bluish for hematoxylin-eosin. The myxoid material was positive for alcian blue, whereas periodic acid-Schiff did not stain this material. No intracytoplasmic mucin was identified. In an immunohistochemical study, the tumor cells were negative for cytokeratin 19. Furthermore, positive staining was observed for thyroglobulin while a negative finding was seen for calcitonin.

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Authors and Affiliations

  1. Department of Surgery, Saitama Medical School, 38 Morohongo, Moroyama-machi, Iruma-gunn, Saitama, 350-0495, Japan

    Saburo Murakami, Hideto Sakata, Katsuhiko Okubo & Yoshitaka Tsuji

  2. Department of Pathology, Saitama Medical School, 38 Morohongo, Moroyama-machi, Iruma-gunn, Saitama, 350-0495, Japan

    Hidekazu Kayano

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  1. Saburo Murakami
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  2. Hideto Sakata
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  4. Yoshitaka Tsuji
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  5. Hidekazu Kayano
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Murakami, S., Sakata, H., Okubo, K. et al. Thyroid Adenoma with Extensive Extracellular Mucin Deposition: Report of a Case. Surg Today 37, 226–229 (2007). https://doi.org/10.1007/s00595-006-3388-1

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  • DOI: https://doi.org/10.1007/s00595-006-3388-1

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