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Effects of Acupressure on Lower Limb Blood Flow for the Treatment of Peripheral Arterial Occlusive Diseases



To investigate the effects of acupressure on lower limb blood flow for the treatment of peripheral arterial occlusive diseases (PAOD).


From February 2004 to February 2005, 30 patients with stage II PAOD underwent measurements of the lower limb blood flow. Six patients (group A) were assigned as controls without any acupoint stimulation, while 24 (group B) underwent stimulation at acupoints by acupressure. The acupoints Yanglingquan (GB34), Zusanli (ST36), Yinlingquan (SP9), and Sanyinjiao (SP6) of the symptomatic lower limbs were stimulated for 3 min. Transcutaneous oximetry (tcPO2) was used to determine the blood flow of the chest wall, bilateral distal crura, and bilateral dorsa of the foot before and during the stimulations at the acupoints.


Group A showed no significant change in the lower limb blood flow. In group B, the tcPO2 values of chest wall, bilateral distal crura, and the dorsum of foot of the stimulated lower limb increased significantly during acupressure (P < 0.01), whereas no significant change was shown in the dorsum of the foot of the non-stimulated lower limb. Moreover, the blood flow of the lower limbs that had undergone an ipsilateral sympathectomy increased significantly (P < 0.01).


Acupressure was found to cause significant increases in the lower limb blood flow of stage II PAOD patients. This treatment modality may therefore be effective for improving the symptoms of such patients.

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  1. 1

    TC Kuo ZS Chen CH Chen FM Ho CW Lin YJ Chen (2004) ArticleTitleThe physiological effect of DE QI during acupuncture Journal of Health Science 50 336–42 Occurrence Handle10.1248/jhs.50.336 Occurrence Handle1:CAS:528:DC%2BD2cXms1Ontbc%3D

    Article  CAS  Google Scholar 

  2. 2

    S Sandberg T Lundeberg L-G Lindberg B Gerdle (2003) ArticleTitleEffects of acupuncture on skin and muscle blood flow in healthy subjects Eur J Appl Physiol 90 114–9 Occurrence Handle12827364

    PubMed  Google Scholar 

  3. 3

    M Bäcker MG Hammes M Valet M Deppe B Conrad TR Tölle et al. (2002) ArticleTitleDifferent modes of manual acupuncture stimulation differentially modulate cerebral blood flow velocity, arterial blood pressure and heart rate in human subjects Neurosci Lett 333 203–6 Occurrence Handle12429383 Occurrence Handle10.1016/S0304-3940(02)01109-6

    PubMed  Article  Google Scholar 

  4. 4

    MW Beal (1999) ArticleTitleAcupuncture and acupressure. Application to woman's reproductive health care J Nurs Midwifery 44 217–30 Occurrence Handle10.1016/S0091-2182(99)00054-3 Occurrence Handle1:STN:280:DyaK1MzgvFGnsg%3D%3D

    Article  CAS  Google Scholar 

  5. 5

    C Stevensen (1997) ArticleTitleShiatu Complement Ther Nurs Midwifery 3 168–70 Occurrence Handle9511647 Occurrence Handle10.1016/S1353-6117(97)80022-4 Occurrence Handle1:STN:280:DyaK1c7nt1KgtQ%3D%3D

    PubMed  Article  CAS  Google Scholar 

  6. 6

    FY Han ZP Wang XJ Dong (1989) ArticleTitleEffects of digital acupressure on the capillary arteriolar flow in cerebral pia mater of the dog J Tradit Chin Med 9 135–9 Occurrence Handle2779277 Occurrence Handle1:STN:280:DyaL1MzotlCksw%3D%3D

    PubMed  CAS  Google Scholar 

  7. 7

    D Felhendler B Lisander (1999) ArticleTitleEffects of non-invasive stimulation of acupoints on the cardiovascular system Complement Ther Med 7 231–4 Occurrence Handle10709307 Occurrence Handle10.1016/S0965-2299(99)80007-7 Occurrence Handle1:STN:280:DC%2BD3c7nsVSrsQ%3D%3D

    PubMed  Article  CAS  Google Scholar 

  8. 8

    FG Quigley IB Faris (1991) ArticleTitleTranscutaneous oxygen tension measurements in the assessment of limb ischaemia Clin Physiol 11 315–20 Occurrence Handle1914435 Occurrence Handle1:STN:280:DyaK38%2Fgs1Ghuw%3D%3D

    PubMed  CAS  Google Scholar 

  9. 9

    SX Qian T Iwai (2000) ArticleTitleIntraoperative evaluation of success and failure of vascular reconstruction by monitoring the transcutaneous partial pressure of oxygen Vasc Surg 34 483–90

    Google Scholar 

  10. 10

    B Fagrell (1995) ArticleTitleAdvances in microcirculation network evaluation: an update Int Microcirc 15 34–40 Occurrence Handle10.1159/000179093

    Article  Google Scholar 

  11. 11

    TW Rooke (1992) ArticleTitleThe use of transcutaneous oximetry in the noninvasive vascular laboratory Int Angiol 11 36–40 Occurrence Handle1522351 Occurrence Handle1:STN:280:DyaK38zpsFegsA%3D%3D

    PubMed  CAS  Google Scholar 

  12. 12

    X Zou D Wang (1990) ArticleTitleComparative study of cerebral infarction treated with acupuncture at 6 acupoints of yang meridian and calan Zhong Xi Yi Jie He Za Zhi 10 199–202 Occurrence Handle2401028 Occurrence Handle1:STN:280:DyaK3czotFyjsA%3D%3D

    PubMed  CAS  Google Scholar 

  13. 13

    L Cheng K Wu Z Qie (1990) ArticleTitleRole of “qi” in reaching affected area using acupuncture in “promoting blood circulation to remove blood stasis Zhong Xi Yi Jie He Za Zhi 10 209–11 Occurrence Handle2401031 Occurrence Handle1:STN:280:DyaK3czotFyjtw%3D%3D

    PubMed  CAS  Google Scholar 

  14. 14

    G Ji L Zhao R Shi Y Liu S Wang F Wu (1996) ArticleTitleEffects of electrical acupuncture on the cerebral blood flow and the pial microcirculatory blood flow in dogs Zhen Ci Yan Jiu 21 43–6 Occurrence Handle9387373 Occurrence Handle1:STN:280:DyaK1c%2FkvVKiuw%3D%3D

    PubMed  CAS  Google Scholar 

  15. 15

    R Shi G Ji L Zhao S Wang Dongjun (1998) ArticleTitleEffects of electroacupuncture and twirling reinforcing-reducing manipulations on volume of microcirculatory blood flow in cerebral pia mater J Tradit Chin Med 18 220–4 Occurrence Handle10453620 Occurrence Handle1:STN:280:DyaK1Mzot12qtA%3D%3D

    PubMed  CAS  Google Scholar 

  16. 16

    H Zeisler W Eppel P Husslein G Bernaschek J Deutinger (2001) ArticleTitleInfluence of acupuncture on Doppler ultrasound in pregnant women Ultrasound Obstet Gynecol 17 229–32 Occurrence Handle11309173 Occurrence Handle10.1046/j.1469-0705.2001.00221.x Occurrence Handle1:STN:280:DC%2BD3M3hvFCrsA%3D%3D

    PubMed  Article  CAS  Google Scholar 

  17. 17

    S Uchida H Hotta F Kagitani Y Aikawa (2003) ArticleTitleOvarian blood flow is reflexively regulated by mechanical afferent stimulation of a hindlimb in nonpregnant anesthetized rats Auton Neurosci 106 91–7 Occurrence Handle12878077 Occurrence Handle10.1016/S1566-0702(03)00073-0

    PubMed  Article  Google Scholar 

  18. 18

    LA Loaiza S Yamaguchi M Ito N Ohshima (2002) ArticleTitleVasodilitation of muscle microvessels induced by somatic afferent stimulation is mediated by calcitonin gene-related peptide release in the rat Neurosci Lett 333 136–40 Occurrence Handle12419499 Occurrence Handle10.1016/S0304-3940(02)01030-3 Occurrence Handle1:CAS:528:DC%2BD38Xotl2ntL8%3D

    PubMed  Article  CAS  Google Scholar 

  19. 19

    A Sato Y Sato M Shimura S Uchida (2000) ArticleTitleCalcitonin gene-related peptide produced skeletal muscle vasodilation following antidromic stimulation of unmyelinated afferents in the dorsal root in rats Neurosci Lett 283 137–40 Occurrence Handle10739894 Occurrence Handle10.1016/S0304-3940(00)00932-0 Occurrence Handle1:CAS:528:DC%2BD3cXitVSrtb8%3D

    PubMed  Article  CAS  Google Scholar 

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Correspondence to Xiangfeng Li.

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Li, X., Hirokawa, M., Inoue, Y. et al. Effects of Acupressure on Lower Limb Blood Flow for the Treatment of Peripheral Arterial Occlusive Diseases. Surg Today 37, 103–108 (2007).

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Key words

  • Acupressure
  • Transcutaneous oximetry (tcPO2)
  • Blood flow
  • Peripheral arterial occlusive disease