Abstract
The familial occurrence of epidermoid cysts of the spleen is rare, with only six cases having ever been reported, to our knowledge. We recently diagnosed epidermoid cysts of the spleen in a mother and son. First, a 15-year-old boy was admitted to our hospital for management of blunt abdominal trauma. Computed tomography (CT) showed a ruptured large splenic cyst with an intraabdominal hematoma. We performed a splenectomy, and histopathological examination confirmed the existence of an epidermoid cyst of the spleen. About 2 years and 6 months later, the family physician found that the patient's 41-year-old mother had a large splenic cyst, and she was referred to our hospital for further investigation. CT showed a 10 × 8 cm cyst occupying most of the spleen. The patient underwent splenectomy, and a pathological diagnosis of an epidermoid cyst of the spleen was confirmed. Although the etiology of epidermoid cysts of the spleen is unclear, this familial occurrence may support the hypothesis of congenital malformation as a result of genetic change.
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References
RH Fowler (1940) ArticleTitleCystic tumors of the spleen Int Abstr Surg 70 213–23
RD McClure WA Altemeier (1942) ArticleTitleCysts of the spleen Ann Surg 116 98–102 Occurrence Handle1:STN:280:DC%2BD2srktlWntQ%3D%3D Occurrence Handle17858077
J Martin (1958) ArticleTitleCongenital splenic cysts Am J Surg 96 302–8 Occurrence Handle13559574 Occurrence Handle1:STN:280:DyaG1c7gt1Khuw%3D%3D Occurrence Handle10.1016/0002-9610(58)90916-4
D Gilmartin (1978) ArticleTitleFamilial multiple epidermoid cysts of the spleen Conn Med 42 297–300 Occurrence Handle648139 Occurrence Handle1:STN:280:DyaE1c7mvVWmsA%3D%3D
LS Ahlgren HE Beardmore (1984) ArticleTitleSolitary epidermoid splenic cysts: occurrence in sibs J Pediatr Surg 19 56–8 Occurrence Handle6699764 Occurrence Handle1:STN:280:DyaL2c7jvVWltg%3D%3D
MW Ragozzino H Singletary R Patrick (1990) ArticleTitleFamilial splenic epidermoid cyst Am J Roentgenol 155 1233–4 Occurrence Handle1:STN:280:DyaK3M%2FltFWjsQ%3D%3D
CAHC Welten ES Sijbrandij (1992) ArticleTitleFamilial nonparasitic splenic cysts Neth J Med 40 236–9 Occurrence Handle1436260 Occurrence Handle1:STN:280:DyaK3s%2FmtlGmsQ%3D%3D
T Iwanaka H Nakanishi Y Tsuchida T Oka T Honna K Shimizu (1995) ArticleTitleFamilial multiple mesothelial cysts of the spleen J Pediatr Surg 30 1743–5 Occurrence Handle8749943 Occurrence Handle1:STN:280:DyaK28zlslCitw%3D%3D Occurrence Handle10.1016/0022-3468(95)90471-9
Y Ito E Shimizu T Miyamoto T Taniguchi K Nakajima T Hara et al. (2002) ArticleTitleEpidermoid cysts of the spleen occurring in sisters Dig Dis Sci 47 619–23 Occurrence Handle11911352 Occurrence Handle10.1023/A:1017984506945
RH Fowler (1953) ArticleTitleNonparasitic benign cystic tumors of the spleen Int Abstr Surg 96 209–27 Occurrence Handle13034324 Occurrence Handle1:STN:280:DyaG3s%2FlvFShsw%3D%3D
YD Ough HR Nash DA Wood (1981) ArticleTitleMesothelial cysts of the spleen with squamous metaplasia Am J Clin Pathol 76 666–9 Occurrence Handle7293981 Occurrence Handle1:STN:280:DyaL38%2Fktlemuw%3D%3D
KF Buerrig (1988) ArticleTitleEpithelial splenic cysts: pathogenesis of the mesothelial and so-called epidermoid cyst of the spleen Am J Surg Pathol 12 275–81
MA Qureshi CD Hafner (1965) ArticleTitleClinical manifestations of splenic cysts, study of 75 cases Am Surg 31 605–8 Occurrence Handle14326973 Occurrence Handle1:STN:280:DyaF2M7jtFKmsA%3D%3D
A Nakao S Saito T Yamano N Takakura H Isozaki K Notohara et al. (1999) ArticleTitleDermoid cyst of the spleen: report of a case Surg Today 29 660–2 Occurrence Handle10452248 Occurrence Handle1:STN:280:DyaK1MznvFeitQ%3D%3D
MF Brown AJ Ross Suffix3rd HC Bishop L Schnaufer MM Ziegler GW Holcomb Suffix3rd (1989) ArticleTitlePartial splenectomy: the preferred alternative for the treatment of splenic cysts J Pediatr Surg 24 694–6 Occurrence Handle2754587 Occurrence Handle1:STN:280:DyaL1MzivVOmsA%3D%3D
RJ Touloukian A Maharaj R Ghoussoub M Reyes (1997) ArticleTitlePartial decapsulation of splenic epithelial cysts: studies on etiology and outcome J Pediatr Surg 32 272–4 Occurrence Handle9044136 Occurrence Handle1:STN:280:DyaK2s7pslSntQ%3D%3D Occurrence Handle10.1016/S0022-3468(97)90193-7
SM Balzan CE Riedner LM Santos MC Pazzinatto PR Fontes (2001) ArticleTitlePosttraumatic splenic cysts and partial splenectomy: report of a case Surg Today 31 262–5 Occurrence Handle11318135 Occurrence Handle1:STN:280:DC%2BD3MvjsV2hsw%3D%3D Occurrence Handle10.1007/s005950170183
M Walz K Metz M Sastry FW Eigler LD Leder (1994) ArticleTitleBenign mesothelial splenic cyst may cause high serum concentration of CA 19-9 Eur J Surg 160 389–91 Occurrence Handle7948360 Occurrence Handle1:STN:280:DyaK2M%2FjsFCntA%3D%3D
T Terada M Yososhima Y Yoshimitsu Y Nakamura (1994) ArticleTitleCarbohydrate antigen 19-9 producing giant epithelial cyst of the spleen in a young woman J Clin Gastroenterol 18 57–61 Occurrence Handle8113588 Occurrence Handle1:STN:280:DyaK2c7lslaqsw%3D%3D Occurrence Handle10.1097/00004836-199401000-00014
K Higaki A Jimi J Watanabe A Kusaba M Kojiro (1998) ArticleTitleEpidermoid cyst of the spleen with CA 19-9 or carcinoembryonic antigen productions. Report of three cases Am J Surg Pathol 22 704–8 Occurrence Handle9630177 Occurrence Handle1:STN:280:DyaK1c3pt1Whuw%3D%3D Occurrence Handle10.1097/00000478-199806000-00007
Y Sakamoto S Yunotani G Edakuni M Mori A Iyama K Miyazaki (1999) ArticleTitleLaparoscopic splenectomy for a giant splenic epidermoid cyst: report of a case Surg Today 29 1268–72 Occurrence Handle10639710 Occurrence Handle1:STN:280:DC%2BD3c7gtlyqsw%3D%3D
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Kubo, M., Yamane, M., Miyatani, K. et al. Familial Epidermoid Cysts of the Spleen: Report of Two Cases. Surg Today 36, 853–856 (2006). https://doi.org/10.1007/s00595-006-3244-3
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DOI: https://doi.org/10.1007/s00595-006-3244-3