References
Yue P, Jing S, Liu L, Ma F, Zhang Y, Wang C et al (2018) Association between mitochondrial DNA copy number and cardiovascular disease: current evidence based on a systematic review and meta-analysis. PLoS ONE 13(11):e0206003
Takemoto K, Deckelbaum RJ, Saito I, Litikmaskul S, Morandi A, Pinelli L et al (2015) Adiponectin/resistin levels and insulin resistance in children: a four country comparison study. Int J Pediatr Endocrinol. https://doi.org/10.1186/1687-9856-2015-2
Chiu RWK, Chan LYS, Lam NYL, Tsui NBY, Ng EKO, Rainer TH et al (2003) Quantitative analysis of circulating mitochondrial DNA in plasma. Clin Chem 49(5):719–726
Nakahira K, Kyung SY, Rogers AJ, Gazourian L, Youn S, Massaro AF et al (2013) Circulating Mitochondrial DNA in Patients in the ICU as a Marker of Mortality: Derivation and Validation. PLoS Med 10(12):e1001577
Knez J, Lakota K, Bozic N, Okrajsek R, Cauwenberghs N, Thijs L et al (2017) Correlation between mitochondrial DNA content measured in myocardium and peripheral blood of patients with non-ischemic heart failure. Genet Test Mol Biomark 21(12):736–741
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflicts of interest.
Ethical standard statement
All the procedures performed in participating children and adolescents were approved by the Verona Ethical Committee Protocol Number: 47460 and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. All participants’ parents or guardians gave their written informed consent for the participation in the study protocol.
Additional information
Managed by Massimo Federici.
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Morandi, A., Zusi, C., Corradi, M. et al. Circulating mitochondrial DNA is decreased in children and adolescents with obesity and/or insulin resistance. Acta Diabetol 57, 623–625 (2020). https://doi.org/10.1007/s00592-019-01471-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00592-019-01471-x