Acta Diabetologica

, Volume 55, Issue 9, pp 885–892 | Cite as

The post-HAPO situation with gestational diabetes: the bright and dark sides

  • Annunziata LapollaEmail author
  • Boyd E. Metzger
Review Article



In 2010, in light of the data coming from the HAPO study, the International Association of Diabetes and Pregnancy Study Groups (IADPSG) proposed a new detection strategy and diagnostic criteria for gestational diabetes based on a one-step approach with a 75 g OGTT. This review analyzes and discusses the bright and dark sides of their application.


The assessment of these recommendations by the international organizations involved in the care of gestational diabetes and a series of observational, retrospective and prospective studies that have been published since 2010 regarding the use of the IADPSG recommendations have been evaluated.


The different international associations involved in the care of pregnancy and of pregnancy complicated by diabetes have not taken an univocal position some of which have accepted them, while others have criticized them. Then, the actual application of the approach recommended by the IADPSG for detecting and diagnosing GDM varies, even at centers that reportedly accept the new diagnostic criteria.


So the challenge lies in making every effort to achieve a global standardization of the strategies for detecting, diagnosing and treating GDM.


Gestational diabetes Diagnostic criteria Maternal outcome Fetal outcome 


Compliance with ethical standards

Conflict of interest

The authors declare no conflict of interest.

Ethical approval

This article does not contain any studies with human participants performed by any of the authors.

Informed consent

For this type of study formal consent is not required.


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Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Diabetology and Dietetics Unit, Department of MedicinePadova UniversityPadovaItaly
  2. 2.Division of Endocrinology, Metabolism and Molecular Medicine, Department of MedicineNorthwestern University Feinberg School of MedicineChicagoUSA

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