Acta Diabetologica

, Volume 54, Issue 11, pp 1061–1063 | Cite as

Acute esophageal necrosis (black esophagus): a case report and literature review

  • Valerio Manno
  • Nicola Lentini
  • Antonio Chirico
  • Maria PerticoneEmail author
  • Luigi Anastasio
Case Report
A 49-year-old male patient, affected by type 2 diabetes mellitus, in oral therapy with metformin, complicated by infected diabetic foot with osteomyelitis of two fingers of the right foot, was admitted to emergency room in sleepy state, with a brief history of fever in previous days. Laboratory study revealed the presence of a septic condition characterized by increased levels of procalcitonin (16,10 ng/ml) and C-reactive protein (96,90 mg/l); lactic acidosis (pH 6.97, HCO 3 3,4 mmol/l, pCO 2 14,7 mmHg, pO 2 162 mmHg, lactacidemia 10 mmol/l); acute renal impairment (creatinine 10.3 mg/dl, ureic nitrogen 299 mg/dl); neutrophilic leucocytosis (WBC 21.51 × 10 3/μl, neutrophils 14.81 × 10 3/μl); hyperglycemia (202 mg/dl) was also present. He was immediately admitted to intensive care unit and treated with hemodialysis by insertion of a central venous cannula. He rapidly got better, and in 2 days he was transferred to internal medicine ward. A rehydratant and empirical antibiotic treatment was...


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


  1. 1.
    Gurvits GE (2010) Black esophagus: acute esophageal necrosis syndrome. World J Gastroenterol 16(26):3219–3225CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Gurvits GE, Shapsis A, Lau N, Gualtieri N, Robilotti JG (2007) Acute esophageal necrosis: a rare syndrome. J Gastroenterol 42:29–38. doi: 10.1007/s00535-006-1974-z CrossRefPubMedGoogle Scholar
  3. 3.
    JuliánGómez L, Barrio J, Atienza R et al (2008) Acute esophageal necrosis. An underdiagnosed disease. Rev Esp Enferm Dig 100(11):701–705Google Scholar
  4. 4.
    Gurvits GE, Cherian K, Nafe Shami M et al (2015) Black esophagus: new insights and multicenter international experience in 2014. Dig Dis Sci 60:444–453. doi: 10.1007/s10620-014-3382-1 CrossRefPubMedGoogle Scholar
  5. 5.
    Shafa S, Sharma N, Keshishian J, Dellon ES (2016) The black esophagus: a rare but deadly disease. ACG Case Rep J 3(2):88–91. doi: 10.14309/crj.2016.9 CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer-Verlag Italia S.r.l. 2017

Authors and Affiliations

  1. 1.Internal Medicine Division“G. Jazzolino” HospitalVibo ValentiaItaly
  2. 2.Gastroenterology and Digestive Endoscopy Service“G. Jazzolino” HospitalVibo ValentiaItaly
  3. 3.Department of Experimental and Clinical MedicineUniversity “Magna Græcia” of CatanzaroCatanzaroItaly

Personalised recommendations