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Achievement of metabolic control among children and adolescents with type 1 diabetes in Spain

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Abstract

Aims

To assess metabolic control in a paediatric T1D population in Spain and analyse the rate of severe acute decompensations and chronic complications.

Methods

Data from patients treated at eight paediatric diabetes units with experienced diabetes teams between June and December 2014 were analysed in an observational prospective study. Variables included: age, sex, diabetes duration, number of follow-up visits/year, anthropometrical data, insulin treatment modalities, mean annual HbA1c and the prevalence of acute and chronic complications. SPSS statistics 21.0 was used.

Results

A total of 853 patients (49.7% female) with a mean age of 12.1 ± 3.7 years were included. Anthropometric data were normal. Mean diabetes duration was 8 ± 3.4 years. Mean outpatient follow-up was 4.7 ± 0.04 visits/year. Twenty-five per cent were on continuous subcutaneous insulin infusion (CSII). Mean HbA1c was 7.3 ± 1% (56 ± 8 mmol/mol) and 66.6% had HbA1c < 7.5% (58 mmol/mol). HbA1c value correlated negatively with age at onset and positively with years of diabetes, number of visits/year and current age (F = 7.06; p = 0.01). Patients on CSII (n = 213) were younger, attended the outpatient clinic more frequently, were diagnosed earlier, had better metabolic control and had presented more severe hypoglycaemic episodes the previous year. The rate of severe decompensation (episodes/100 patients/year) was ketoacidosis 1.5 and severe hypoglycaemia 4.5. The prevalence of chronic complications was very low.

Conclusions

Our data describe the good compliance of paediatric T1D patients treated at eight paediatric units in Spain following international standards of metabolic control.

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Author information

Authors and Affiliations

  1. Paediatric Endocrinology, Hospital Universitario de Cruces, CIBERDEM, CIBERER, BIOCRUCES, Plaza Cruces s/n, 48903, Barakaldo, Bizkaia, Spain

    Itxaso Rica

  2. Paediatric Endocrinology, Hospital General Universitario de Alicante, Pintor Baeza 11, 03010, Alicante, Spain

    Andrés Mingorance

  3. Paediatric Endocrinology Unit. Paediatric Service, Hospital Infantil, HHUU Virgen Rocío, Avda Marques Luca de Tena s/n, Seville, Spain

    Ana Lucía Gómez-Gila

  4. Paediatric Endocrinology Unit, Paediatric Service, Growth and Development Research Unit, Vall d’Hebron Research Institute (VHIR), Hospital Vall d’Hebron, CIBERER, Instituto de Salud Carlos III, Ps. Vall d´Hebron 119-129, 08035, Barcelona, Spain

    María Clemente

  5. Paediatric Endocrinology, Hospital Infantil La Paz, Pº Castellana 261, 28046, Madrid, Spain

    Isabel González

  6. Paediatric Endocrinology, Hospital Universitario Son Espases, Carretera Valldemosa, 79, 07010, Palma de Mallorca, Spain

    María Caimari

  7. Paediatric Endocrinology Unit, Severo Ochoa University Hospital, 28911, Leganés, Madrid, Spain

    Beatriz García-Cuartero

  8. Paediatric Endocrinology and Diabetes Unit, Ramón y Cajal University Hospital, Cta. Colmenar Viejo 9, 100, 28034, Madrid, Spain

    Raquel Barrio

Authors
  1. Itxaso Rica
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  2. Andrés Mingorance
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  3. Ana Lucía Gómez-Gila
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  4. María Clemente
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  5. Isabel González
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  6. María Caimari
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  7. Beatriz García-Cuartero
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  8. Raquel Barrio
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Corresponding author

Correspondence to María Clemente.

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Ethical standard

This study has been approved by the institutional research ethics committee and has been performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

Human and animal rights

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008.

Informed consent

Informed consent was obtained from all patients for being included in the study.

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Rica, I., Mingorance, A., Gómez-Gila, A.L. et al. Achievement of metabolic control among children and adolescents with type 1 diabetes in Spain. Acta Diabetol 54, 677–683 (2017). https://doi.org/10.1007/s00592-017-0991-0

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  • DOI: https://doi.org/10.1007/s00592-017-0991-0

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