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The severity of coronary atherosclerosis in diabetic and non-diabetic metabolic syndrome patients diagnosed according to different criteria and undergoing elective angiography

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Abstract

Our aim in this study was to evaluate the relationship between metabolic syndrome (MS) as defined by different criteria and the severity of coronary lesions in a sample of diabetic and non-diabetic patients undergoing elective coronary angiography. All patients had blood and urine tests, physical examinations were performed before angiography, and finally they were classified based on three criteria (World Health Organisation-WHO, Adult Treatment Panel-ATP III and International Diabetes Federation-IDF). Eighty-eight patients were diabetic, and 96 patients were non-diabetic. Among all patients, diabetics had significantly higher Gensini scores (P < 0.001). According to WHO criteria (P = 0.005) and IDF criteria (P = 0.015) metabolic syndrome patients had higher Gensini scores, but for ATP III criteria difference was not significant. When we evaluated diabetics and non-diabetics separately, non-diabetic patients with MS had significantly higher scores with WHO definition (P = 0.015) and mildly higher but not significant values with other MS criteria (P = 0.057 for both IDF and ATP III). Neither any one of MS components nor gender revealed significant relationship with coronary disease severity. In our study with a cohort of Turkish patients undergoing elective coronary angiography; we concluded that MS should be taken into consideration, especially in non-diabetic patients.

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Acknowledgments

This study has been performed with the financial support from Ankara Guven Hospital.

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Authors and Affiliations

  1. Department of Endocrinology and Metabolic Diseases, Ufuk University, Dr. Ridvan Ege Hospital, Mevlana Bulvari 86-88, 06520, Ankara, Turkey

    S. Ertek

  2. Department of Internal Medicine, Aging and Kidney Diseases, Bologna University, Bologna, Italy

    A. F. Cicero

  3. Department of Endocrinology and Metabolic Diseases, Guven Hospital, Ankara, Turkey

    M. Cesur

  4. Faculty of Science and Letters, Department of Statistics and Computer Science, Baskent University, Ankara, Turkey

    M. Akcil

  5. Department of Internal Medicine, Guven Hospital, Ankara, Turkey

    U. Avcioglu

  6. Department of Cardiology, Guven Hospital, Ankara, Turkey

    T. Altuner Kayhan & M. E. Korkmaz

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  1. S. Ertek
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Correspondence to S. Ertek.

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Ertek, S., Cicero, A.F., Cesur, M. et al. The severity of coronary atherosclerosis in diabetic and non-diabetic metabolic syndrome patients diagnosed according to different criteria and undergoing elective angiography. Acta Diabetol 48, 21–27 (2011). https://doi.org/10.1007/s00592-010-0211-7

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  • DOI: https://doi.org/10.1007/s00592-010-0211-7

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