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Comparison of baseline demographics and risk factors for aseptic loosening following primary total elbow arthroplasty

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European Journal of Orthopaedic Surgery & Traumatology Aims and scope Submit manuscript

Abstract

Background

Aseptic loosening is a feared complication following total elbow arthroplasty (TEA); however, literature regarding factors that may contribute to this complication is limited. The aims of this investigation were to: (1) compare baseline demographics of patients who developed aseptic loosening following primary TEA; and (2) identify patient-specific risk factors for the development of loosening.

Methods

Retrospective analysis using a nationwide claims database was performed to identify patients who underwent primary TEA and developed aseptic loosening within 2 years (study n = 307, control n = 10,741). Multivariate regression analysis generated odds ratio (OR), 95% confidence interval (95% CI), and p-value of risk factors. p < 0.05 was considered statistically significant.

Results

Patients who developed aseptic loosening had significant differences in numerous demographics, including age (p = 0.0001), sex (p = 0.0251), and various comorbid conditions such as obesity (15.96% vs. 8.36%, p < 0.0001). Furthermore, the risk factors most associated with aseptic loosening were obesity (OR 1.65, 95% CI 1.18–2.28, p = 0.002), male sex (OR 1.51, 95% CI 1.13–2.00, p = 0.004), and concomitant opioid use disorder (OR 1.58, 95% CI 1.14–2.15, p = 0.004).

Discussion

This study is the first to identify demographics and patient-related risk factors associated with aseptic loosening following primary TEA. This evidence could be applied to the clinical setting in order to educate at-risk patients of this potential complication as well as inform their post-operative clinical management.

Level of evidence

Level III: Prognostic

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Acknowledgments

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Funding

No funding was used for this study.

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Authors and Affiliations

  1. Department of Orthopedic Surgery, Maimonides Medical Center, 927 49th Street, Brooklyn, NY, 11219, USA

    Harriet Prior, Zenab Jamil, Ariel N. Rodriguez, Samuel J. Swiggett, Miriam D. Weisberg, Afshin E. Razi & Jack Choueka

  2. College of Medicine, State University of New York Downstate, Brooklyn, NY, USA

    Harriet Prior & Zenab Jamil

Authors
  1. Harriet Prior
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  2. Zenab Jamil
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  3. Ariel N. Rodriguez
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  4. Samuel J. Swiggett
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  5. Miriam D. Weisberg
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  6. Afshin E. Razi
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  7. Jack Choueka
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Correspondence to Ariel N. Rodriguez.

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Prior, H., Jamil, Z., Rodriguez, A.N. et al. Comparison of baseline demographics and risk factors for aseptic loosening following primary total elbow arthroplasty. Eur J Orthop Surg Traumatol 33, 3153–3158 (2023). https://doi.org/10.1007/s00590-023-03550-w

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  • DOI: https://doi.org/10.1007/s00590-023-03550-w

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