Abstract
Introduction
Studies evaluating the association of dementia in patients undergoing total hip arthroplasty (THA) for femoral neck fractures are limited. The aim was to investigate whether patients who have dementia undergoing THA for femoral neck fractures have higher rates of (1) in-hospital lengths of stay (LOS); 2) complications (medical and prostheses-related); and 3) healthcare expenditures.
Methods
A retrospective query using the PearlDiver database from January 1st, 2005 to March 31st, 2014 to identify patients with dementia undergoing primary total hip arthroplasty for the treatment of femoral neck fractures was performed. Dementia patients were 1:5 ratio matched to controls which yielded 22,758 patients in the study with (n = 3,798) and without (n = 18,960) dementia. Primary outcomes included comparing LOS, complications, and costs. A logistic regression was constructed to calculate the odds-ratios (OR) of dementia on complications. A p-value less than 0.004 was significant.
Results
Dementia patients had longer LOS (7-days vs. 6-days, p < 0.0001) and higher incidence and odds of medical complications (41.52 vs. 17.77%; OR 3.76, p < 0.0001), including cerebrovascular events (5.66 vs. 1.64%; OR 2.35, p < 0.0001), pneumoniae (9.98 vs. 3.82%; OR 1.82, p < 0.0001), and acute kidney injury (8.37 vs. 3.27%; OR 1.62, p < 0.0001). Study group patients had higher frequency of prostheses-related complications (9.53 vs. 8.31%; OR: 1.16, p = 0.012). The study group had greater total healthcare expenditures ($28,879.57 vs. $26,234.10, p < 0.0001) when analyzing ninety-day episode of care charges.
Conclusion
Patients with dementia undergoing THA due to femoral neck fracture have increased LOS, medical and prostheses-related complications, and cost of care compared to their counterparts.
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References
Raz L, Knoefel J, Bhaskar K (2016) The neuropathology and cerebrovascular mechanisms of dementia. J Cereb Blood Flow Metab 36:172–186. https://doi.org/10.1038/JCBFM.2015.164
Gale SA, Acar D, Daffner KR (2018) Dementia. Am J Med 131:1161–1169. https://doi.org/10.1016/J.AMJMED.2018.01.022
Baumgart M, Snyder HM, Carrillo MC et al (2015) Summary of the evidence on modifiable risk factors for cognitive decline and dementia: a population-based perspective. Alzheimers Dement 11:718–726. https://doi.org/10.1016/J.JALZ.2015.05.016
Jordan BC, Brungardt J, Reyes J et al (2018) Dementia as a predictor of mortality in adult trauma patients. Am J Surg 215:48–52. https://doi.org/10.1016/J.AMJSURG.2017.07.012
Petis S, Howard JL, Lanting BL, Vasarhelyi EM (2015) Surgical approach in primary total hip arthroplasty: anatomy, technique and clinical outcomes. Can J Surg 58:128–139. https://doi.org/10.1503/CJS.007214
Hernandez NM, Cunningham DJ, Jiranek WA et al (2020) Total hip arthroplasty in patients with dementia. J Arthroplast 35:1667-1670.e2. https://doi.org/10.1016/J.ARTH.2020.01.070
Hernandez NM, Cunningham DJ, Jiranek WA et al (2020) Total knee arthroplasty in patients with dementia. J Knee Surg. https://doi.org/10.1055/S-0040-1712086
Kim HC, An SB, Jeon H et al (2021) Preoperative cognitive impairment as a predictor of postoperative outcomes in elderly patients undergoing spinal surgery for degenerative spinal disease. J Clin Med. https://doi.org/10.3390/JCM10071385
Muir SW, Yohannes AM (2009) The impact of cognitive impairment on rehabilitation outcomes in elderly patients admitted with a femoral neck fracture: a systematic review. J Geriatr Phys Ther 32:24–32. https://doi.org/10.1519/00139143-200932010-00006
Mosk CA, Mus M, Vroemen JPAM et al (2017) Dementia and delirium, the outcomes in elderly hip fracture patients. Clin Interv Aging 12:421–430. https://doi.org/10.2147/CIA.S115945
Jämsen E, Peltola M, Puolakka T et al (2015) Surgical outcomes of hip and knee arthroplasties for primary osteoarthritis in patients with Alzheimer’s disease: a nationwide registry-based case-controlled study. Bone Jt J 97-B:654–661. https://doi.org/10.1302/0301-620X.97B5.34382/ASSET/IMAGES/LARGE/34382-GALLEYFIG3.JPEG
Möllers T, Stocker H, Wei W et al (2019) Length of hospital stay and dementia: a systematic review of observational studies. Int J Geriatr Psychiatry 34:8–21. https://doi.org/10.1002/GPS.4993
Heng M, Eagen CE, Javedan H et al (2016) Abnormal mini-cog is associated with higher risk of complications and delirium in geriatric patients with fracture. J Bone Jt Surg Am 98:742–750. https://doi.org/10.2106/JBJS.15.00859
Tsuda Y, Yasunaga H, Horiguchi H et al (2015) Association between dementia and postoperative complications after hip fracture surgery in the elderly: analysis of 87,654 patients using a national administrative database. Arch Orthop Trauma Surg 135:1511–1517. https://doi.org/10.1007/S00402-015-2321-8
Sue Eisenstadt E (2010) Dysphagia and aspiration pneumonia in older adults. J Am Acad Nurse Pract 22:17–22. https://doi.org/10.1111/J.1745-7599.2009.00470.X
Zachwieja E, Butler AJ, Grau LC et al (2019) The association of mental health disease with perioperative outcomes following femoral neck fractures. J Clin Orthop trauma 10:S77–S83. https://doi.org/10.1016/J.JCOT.2019.01.002
Buller LT, Best MJ, Klika AK, Barsoum WK (2015) The influence of psychiatric comorbidity on perioperative outcomes following primary total hip and knee arthroplasty; a 17-year analysis of the national hospital discharge survey database. J Arthroplast 30:165–170. https://doi.org/10.1016/J.ARTH.2014.08.034
Kapadia BH, McElroy MJ, Issa K et al (2014) The economic impact of periprosthetic infections following total knee arthroplasty at a specialized tertiary-care center. J Arthroplast 29:929–932. https://doi.org/10.1016/J.ARTH.2013.09.017
Holloway RG, Witter DM, Lawton KB et al (1996) Inpatient costs of specific cerebrovascular events at five academic medical centers. Neurology 46:854–860
Malcolm TL, Knezevic NN, Zouki CC, Tharian AR (2020) Pulmonary complications after hip and knee arthroplasty in the United States, 2004–2014. Anesth Analg 130:917–924. https://doi.org/10.1213/ANE.0000000000004265
Viramontes O, Luan Erfe BM, Erfe JM et al (2019) Cognitive impairment and postoperative outcomes in patients undergoing primary total hip arthroplasty: a systematic review. J Clin Anesth 56:65–76. https://doi.org/10.1016/J.JCLINANE.2019.01.024
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Ahluwalia, S.S., Lugo, J.D., Gordon, A.M. et al. The association of dementia on perioperative complications following primary total hip arthroplasty for femoral neck fractures. Eur J Orthop Surg Traumatol 33, 971–976 (2023). https://doi.org/10.1007/s00590-022-03236-9
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DOI: https://doi.org/10.1007/s00590-022-03236-9