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What’s new in the management of metastatic bone disease

Abstract

Metastatic bone disease is a common complication of malignant tumours. As cancer treatment improves the overall survival of patients, the number of patients with bone metastases is expected to increase. The treatments for bone metastases include surgery, radiotherapy, and bone-modifying agents, with patients with a short expected prognosis requiring less invasive treatment. Patients with metastatic bone disease show greatly varying primary tumour histology, metastases sites and numbers, and comorbidities. Therefore, randomised clinical trials are indispensable to compare treatments for these patients. This editorial reviews recent findings on the diagnosis and prognosis prediction and discusses the current treatment of patients with metastatic bone disease.

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ST and AFM performed the literature search and wrote the manuscript. CE and AK revised the manuscript. All authors have read and approved the final manuscript.

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Correspondence to Shinji Tsukamoto.

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Tsukamoto, S., Errani, C., Kido, A. et al. What’s new in the management of metastatic bone disease. Eur J Orthop Surg Traumatol 31, 1547–1555 (2021). https://doi.org/10.1007/s00590-021-03136-4

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Keywords

  • Metastatic bone disease
  • Prognosis
  • Cancer
  • Cementoplasty
  • Radiotherapy
  • Electrochemotherapy