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Transfusion timing relative to surgery does not impact outcomes in hip fracture patients

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European Journal of Orthopaedic Surgery & Traumatology Aims and scope Submit manuscript

Abstract

Purpose

The purpose of this study is to determine the effects of blood transfusion timing in hip fracture patients.

Methods

A consecutive series of hip fracture patients 55 years and older who required a blood transfusion during hospitalization were reviewed for demographic, injury, clinical outcome, and cost information. A validated risk predictive score (STTGMA) was calculated for each patient. Patients were stratified to preoperative, intraoperative, or postoperative first transfusion cohorts. The intraoperative and postoperative cohorts were matched by STTGMA, sex, and procedure to the preoperative cohort. Baseline patient characteristics and outcomes were compared before and after matching.

Results

Prior to matching, the preoperative cohort was more often male (p < 0.001) with increased Charlson comorbidity index (p = 0.012), ASA class (p < 0.002), STTGMA (p < 0.001), total transfused volume (p = 0.002), incidence of inpatient mortality (p = 0.045), myocardial infarction (p = 0.005) and cardiac arrest (p = 0.014). After matching, the preoperative cohort had increased total transfused volume (p = 0.015) and decreased pneumonia incidence (p = 0.040).

Conclusion

Matching STTGMA score, sex, and procedure results in non-inferior outcomes among hip fracture patients receiving preoperative first blood transfusions compared to intraoperative and postoperative transfusions.

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Funding

No funding was received for conducting this study.

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Authors and Affiliations

  1. Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, New York, NY, USA

    Rown Parola, Sanjit R. Konda, Cody R. Perskin, Abhishek Ganta & Kenneth A. Egol

  2. Department of Orthopedic Surgery, Jamaica Hospital Medical Center, Jamaica, NY, USA

    Sanjit R. Konda, Abhishek Ganta & Kenneth A. Egol

Authors
  1. Rown Parola
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  2. Sanjit R. Konda
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  3. Cody R. Perskin
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  4. Abhishek Ganta
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  5. Kenneth A. Egol
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Corresponding author

Correspondence to Kenneth A. Egol.

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The authors have no relevant financial or non-financial interests to disclose.

Ethics approval

The study was approved by the NYU Grossman School of Medicine Institutional Review Board, New York, NY. The IRB Number is i20-01766.

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A Waiver of Consent was approved by the NYU Grossman School of Medicine Institutional Review Board.

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Parola, R., Konda, S.R., Perskin, C.R. et al. Transfusion timing relative to surgery does not impact outcomes in hip fracture patients. Eur J Orthop Surg Traumatol 32, 725–732 (2022). https://doi.org/10.1007/s00590-021-03033-w

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  • DOI: https://doi.org/10.1007/s00590-021-03033-w

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