Abstract
Background
The use of articulating spacers, molded or prefabricated, becomes difficult in case of severe bone losses. Our idea was to customize the Molded Articulating Cement Spacers with cement stem extensions and if necessary metaphyseal cement augmentations in order to use them also in case of major bone defects.
Methods
Fifty-four knees in fifty-three patients undergoing 2-stage exchange arthroplasty were divided in 4 groups, treated with 4 different types of spacers (Static, articulating molded, customized molded and metal on Poly) and evaluated in terms of Range of Motion (ROM), Knee Society Score (KSS), patients’ related outcome measures (PROMs), rate of complication and ease of the surgical exposure at the time of reimplantation.
Results
At final follow-up, no statistical differences in terms of ROM and KSS were found between the articulating groups. Static Spacers showed statistically significant lower results both in terms of ROM and KSS comparing to the other 3 groups (P < 0.05). Considering PROMs, statistically better outcomes for all articulating spacers were found both when spacer was in place and at final follow-up comparing to the static spacers group (P < 0.05). No statistically significant difference was found between the 3 articulating spacers groups. Radiographic analysis did not show signs of loosening, migration or major bone loss.
Conclusions
Customized Intraoperatively Molded Articulating Cement Spacers are a safe solution for two-stage revisions TKA with major bone defects and may provide a better quality of life for patients when in place comparing to static ones.
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References
Pangaud C, Ollivier M, Argenson JN (2019) Outcome of single-stage versus two-stage exchange for revision knee arthroplasty for chronic periprosthetic infection. EFORT Open Rev 4:495–502. https://doi.org/10.1302/2058-5241.4.190003
Romanò CL, Gala L, Logoluso N et al (2012) Two-stage revision of septic knee prosthesis with articulating knee spacers yields better infection eradication rate than one-stage or two-stage revision with static spacers. Knee Surg Sports TraumatolArthrosc 20:2445–2453
Xu C, Goswami K, Li WT et al (2020) Is Treatment of periprosthetic joint infection improving over time? J Arthroplasty. https://doi.org/10.1016/j.arth.2020.01.080
Gehrke T, Alijanipour P, Parvizi J, et al The management of an infected total knee arthroplasty. https://doi.org/https://doi.org/10.1302/0301-620X.97B10
George DA, Haddad FS (2014) Surgical management of periprosthetic joint infections: two-stage exchange. J Knee Surg 27:279–282
Shahpari O, Mousavian A, Elahpour N et al (2020) The use of antibiotic impregnated cement spacers in the treatment of infected total joint replacement: Challenges and achievements. Archives Bone Joint Surgy 8:11–20
Guild GN, Wu B, Scuderi GR (2014) Articulating Vs. Static Antibiotic Impregnated Spacers in revision total knee arthroplasty for sepsis. A systematic review. J Arthroplasty 29:558–563. https://doi.org/10.1016/j.arth.2013.08.013
Spivey JC, Guild GN, Scuderi GR (2017) Use of articulating spacer technique in revision total knee arthroplasty complicated by sepsis: a systematic meta-analysis. Orthopedics 40:212–220
Voleti PB, Baldwin KD, Lee GC (2013) Use of static or articulating spacers for infection following total knee arthroplasty. J Bone Joint Surg–Series A 95:1594–1599. https://doi.org/10.2106/JBJS.L.01461
Classen T, von Knoch M, Wernsmann M et al (2014) Functional interest of an articulating spacer in two-stage infected total knee arthroplasty revision. Orthopaedics Traumatol: Surg Res 100:409–412. https://doi.org/10.1016/j.otsr.2014.01.010
Charette RS, Melnic CM (2018) Two-stage revision arthroplasty for the treatment of prosthetic joint infection. Curr Rev Musculoskeletal Med 11:332–340
Shaikh AA, Ha CW, Park YG, Park YB (2014) Two-stage approach to primary TKA in infected arthritic knees using intraoperativelymolded articulating cement spacers. ClinOrthopRelat Res 472:2201–2207. https://doi.org/10.1007/s11999-014-3545-6
van Thiel GS, Berend KR, Klein GR et al (2011) Intraoperative molds to create an articulating spacer for the infected knee arthroplasty. Clinical orthopaedics and related research. Springer, New York LLC, pp 994–1001
Goltz DE, Sutter EG, Bolognesi MP, Wellman SS (2018) Outcomes of articulating spacers with autoclaved femoral components in total knee arthroplasty infection. J Arthroplasty 33:2595–2604. https://doi.org/10.1016/j.arth.2018.03.059
Lee BJ, Kyung HS, Yoon SD (2015) Two-stage revision for infected total knee arthroplasty: based on autoclaving the recycled femoral component and intraoperative molding using antibiotic-impregnated cement on the tibial side. CiOS Clinics in OrthopedicSurg 7:310–317. https://doi.org/10.4055/cios.2015.7.3.310
Benazzo F, Rossi SMP, Combi A et al (2016) Knee replacement in chronic post-traumatic cases. EFORT Open Rev. https://doi.org/10.1302/2058-5241.1.000025
Benazzo F, Rossi SMP (2012) The trivector approach for minimally invasive total knee arthroplasty: a technical note. J Orthopaedics Traumatol. https://doi.org/10.1007/s10195-012-0197-8
Hofmann AA, Goldberg T, Tanner AM, Kurtin SM (2005) Treatment of infected total knee arthroplasty using an articulating spacer: 2- to 12-year experience. ClinOrthopRelat Res. https://doi.org/10.1097/01.blo.0000149241.77924.01
Preobrazhensky PM, Bozhkova SA, Kazemirsky AV et al (2019) Functional outcome of two-stage reimplantation in patients with periprosthetic joint infection after primary total knee arthroplasty. IntOrthop 43:2503–2509. https://doi.org/10.1007/s00264-019-04296-z
Sai CH, Hsu HC, Chen HY et al (2019) A preliminary study of the novel antibiotic-loaded cement computer-aided design-articulating spacer for the treatment of periprosthetic knee infection 11 Medical and Health Sciences 1103 Clinical Sciences. J OrthopaedicSurg Res. https://doi.org/10.1186/s13018-019-1175-0
Ding H, Yao J, Chang W, Liu F (2017) Comparison of the efficacy of static versus articular spacers in two-stage revision surgery for the treatment of infection following total knee arthroplasty: a meta-analysis. J Orthopaedic Surg Res. https://doi.org/10.1186/s13018-017-0644-6
Pivec R, Naziri Q, Issa K et al (2014) Systematic review comparing static and articulating spacers used for revision of infected total knee arthroplasty. J Arthroplasty. https://doi.org/10.1016/j.arth.2013.07.041
Lichstein P, Su S, Hedlund H et al (2016) Treatment of periprosthetic knee infection with a two-stage protocol using static spacers. ClinOrthopRelat Res 474:120–125. https://doi.org/10.1007/s11999-015-4443-2
von Schéele B, Martin RD, Gilsenan AW et al (2009) Histologi the European postmarketing adult Osteosarcoma surveillance study: characteristics of patients a preliminary report. ActaOrthop 80:67–74. https://doi.org/10.1080/17453670902805064
Krishnan SP, Dawood A, Richards R et al (2012) A review of rapid prototyped surgical guides for patient-specific total knee replacement. J Bone Joint Surg Series–B 94:1457–1461
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This study obtained IRB Approval (No. 2015001968), and written consent was obtained from all patients.
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Rossi, S.M.P., Medetti, M., Perticarini, L. et al. Customized intraoperatively molded articulating cement spacers for two-stage revisions TKA with major bone defects. Eur J Orthop Surg Traumatol 31, 1121–1128 (2021). https://doi.org/10.1007/s00590-020-02844-7
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DOI: https://doi.org/10.1007/s00590-020-02844-7