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Medical morbidities in people following hip and knee arthroplasty: data from the Osteoarthritis Initiative

  • Original Article • HIP - ARTHROPLASTY
  • Published:
European Journal of Orthopaedic Surgery & Traumatology Aims and scope Submit manuscript

Abstract

Background

Total hip (THA) and knee (TKA) arthroplasty are common orthopaedic procedures most frequently for older people. Whilst it is known that this older population frequently present with medical morbidities, no studies have previously documented the prevalence of such morbidities in people who have undergone THA or TKA. The purpose of this study was to determine the prevalence and what factors are in association with the presentation of medical morbidities in these populations.

Methods

Data from the Osteoarthritis Initiative, a population-based observational study, was assessed. In total 419 people who had undergone a THA or TKA were assessed to determine the prevalence of recorded morbidities within 12 months post-arthroplasty. All medical morbidities were then assessed using univariate and then multivariate logistic regression analysis to identify factors influencing the presentation of specific morbidities at 12 months following THA or TKA.

Results

The most common medical morbidities included: osteoporosis (16 %), mild-to-moderate depression (8 %), cancer (8 %), diabetes (6 %), history of stroke or TIA (6 %) and asthma (5 %). The medical morbidities demonstrated are similar between those who undergo THA and TKA. Only gender and ethnic origin were identified as statistically significant predictors of medical morbidities in these populations. Gender was a predictor of history of heart failure, whilst ethnic origin significantly predicted depression.

Conclusions

People who undergo THA or TKA may present with a variety of medical morbidities. Accordingly consideration should be made on how to encourage the adoption and maintenance of physical activity and healthy lifestyle choices for this population.

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Acknowledgments

We would like to thank Professor Andy Jones, Professor in Public Health, Norwich Medical School, the University of East Anglia, for reviewing this paper during its preparation.

Funding

The OAI is a public–private partnership comprised of five contracts (N01-AR-2-2258; N01-AR-2-2259; N01-AR-2-2260; N01-AR-2-2261; N01-AR-2-2262) funded by the National Institutes of Health, a branch of the Department of Health and Human Services, and conducted by the OAI Study Investigators. Private funding partners include Merck Research Laboratories; Novartis Pharmaceuticals Corporation, GlaxoSmithKline; and Pfizer, Inc. Private sector funding for the OAI is managed by the Foundation for the National Institutes of Health.

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Authors and Affiliations

  1. Faculty of Medicine and Health Sciences, School of Health Sciences, Queen’s Building, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK

    Toby O. Smith

  2. Physiotherapy Department, St. Bartholomew’s Hospital, London, UK

    Florence Penny

  3. Norwich Medical School, University of East Anglia, Norwich, UK

    Robert Fleetcroft

Authors
  1. Toby O. Smith
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  2. Florence Penny
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  3. Robert Fleetcroft
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Corresponding author

Correspondence to Toby O. Smith.

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Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Ethics approval

Committee on Human Research, University of California, San Francisco (IRB Approval Number 10-00532 Approved 10th March 2015).

Data sharing statement

This manuscript was prepared using an OAI public use data set and does not necessarily reflect the opinions or views of the OAI investigators, the NIH, or the private funding partners.

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Smith, T.O., Penny, F. & Fleetcroft, R. Medical morbidities in people following hip and knee arthroplasty: data from the Osteoarthritis Initiative. Eur J Orthop Surg Traumatol 26, 99–106 (2016). https://doi.org/10.1007/s00590-015-1713-3

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  • DOI: https://doi.org/10.1007/s00590-015-1713-3

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