Dimitrios Kardamakis; Vassilios Vassiliou; Edward Chow (Eds.): Bone metastases: a translational and clinical approach
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This book is the 12th volume in the series Cancer Metastasis: Biology and Treatment. The aim of the book is to provide both an introduction and reference book on the field of metastatic bone disease.
The authorship is truly international. The chapters are in consistent format and blend well together.
The book is split into four sections: fundamental concepts, imaging, therapeutic strategies and assessment of response.
Fundamental concepts cover anatomy, pathophysiology, angiogenesis, natural history and bone biomarkers and provide a very detailed review of the current state of knowledge.
Imaging covers in detail the emerging roles of PET–CT and MRI in metastatic bone disease as well as the more conventional imaging approaches.
Therapeutic strategies focus on radiotherapy, bisphosphonates (including a separate chapter on osteonecrosis of the jaw), surgery, chemotherapy, hormone therapy and radionuclide therapy.
Assessment of response covers clinical, radiological and marker response as well as looking at pain and the development of a quality of life assessment for patients with bone metastases.
Each chapter is extensively referenced.
The book is very clear and comprehensive. I think the book achieves its twin aims and is an extremely good reference book for those people researching and managing skeletal metastases. It will appeal to researchers, orthopaedic surgeons, oncologists and students alike but is more likely to be seen as a reference book than one to be in the individual’s library.