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Acute lymphoblastic leukemia presenting with thigh pain in a 2 year old: a case report with clinico-pathologic correlation

Leucémie lymphoblastique aiguë avec douleur de cuisse

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European Journal of Orthopaedic Surgery & Traumatology Aims and scope Submit manuscript

Abstract

Musculoskeletal pain may be the initial presentation of various malignancies. Leukemia presenting with bone pain is not uncommon. This case illustrates that periosteal reaction can be one of the initial radiological signs of leukemia and an immunohistochemical study with karyotyping is necessary to confirm the diagnosis.

Résumé

Des douleurs musculo-squelettiques initient souvent divers tumeurs malignes. Une leucémie débutant ainsi n’est pas chose rare. Ce cas démontre qu’une réaction périostée peut être l’un des premiers signes radiologiques d’une leucémie. Une étude immuno-histo-chimique avec caryotype est nécessaire pour faire le diagnostic.

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Authors and Affiliations

  1. Orthopaedic Division, Nemours Children’s Clinic, 83 W. Columbia Street, Orlando, FL, 32806, USA

    Varatharaj Mounasamy & José A. Herrera-Soto

  2. Department of Pathology, Orlando Regional Medical Center, Orlando, FL, USA

    Jason Savell

  3. Hematology Division, Nemours Children’s Clinic, Orlando, FL, USA

    Vincent Giusti

Authors
  1. Varatharaj Mounasamy
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  2. Jason Savell
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  3. Vincent Giusti
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  4. José A. Herrera-Soto
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Corresponding author

Correspondence to Varatharaj Mounasamy.

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Mounasamy, V., Savell, J., Giusti, V. et al. Acute lymphoblastic leukemia presenting with thigh pain in a 2 year old: a case report with clinico-pathologic correlation. Eur J Orthop Surg Traumatol 16, 372–375 (2006). https://doi.org/10.1007/s00590-006-0106-z

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  • DOI: https://doi.org/10.1007/s00590-006-0106-z

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