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Trends in infectious spondylitis from 2000 to 2020

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Abstract

Purpose

This study aimed to investigate the trends in infectious spondylitis over the past two decades.

Methods

We included 157 cases, from 2000 to 2020, of infectious spondylitis. The cases were divided into two groups: 00 (cases during 2000–2009; 82 cases:) and 10 (cases during 2010–2020; 75 cases) groups. Patients’ age, sex, causative organism, and localization were examined and compared between the two groups.

Results

The proportions of women in the 00 and 10 groups were 30.5% and 38.7%, respectively, with no significant difference (P = 0.28). The average age was significantly higher in the 10 group (72.6 years) than in the 00 group (68.8 years; P < 0.01). A compromised host was the cause of infection in 52.4% and 36.0% of the patients in the 00 and 10 groups, respectively, showing a significant difference. The bacterial identification rates were 70.1% and 77.3% in the 00 and 10 groups, respectively (P < 0.01), and the genus Staphylococcus was the most common bacteria. The proportions of resistant bacteria such as methicillin-resistant Staphylococcus aureus in the 00 and 10 groups were 27.3% and 6.7%, respectively (P < 0.01). Conversely, infectious diseases caused by indigenous bacteria in the oral cavity and intestines were more common in the 10group (37.8%) than in the 00 group (13.0%), showing a significant difference (P < 0.01).

Conclusion

Recently, infections caused by indigenous bacteria in the oral cavity and intestines have increased more than those caused by resistant bacteria over the past two decade.

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Data availability

The data that support the findings of this study are available from the corresponding author, Shinji Tanishima, upon reasonable request.

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Funding

This study doesn’t have any Fundings.

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Authors and Affiliations

  1. Division of Orthopedic Surgery, Department of Sensory and Motor Organs, School of Medicine, Faculty of Medicine, Tottori University, 36–1 Nishi-cho, Yonago, Tottori, 683-8504, Japan

    Shinji Tanishima, Tokumitsu Mihara, Chikako Takeda, Satoshi Fujiwara & Hideki Nagashima

Authors
  1. Shinji Tanishima
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  2. Tokumitsu Mihara
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  3. Chikako Takeda
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  4. Satoshi Fujiwara
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  5. Hideki Nagashima
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Contributions

S.T. designed the study, the main conceptual ideas, and the proof outline. C.T, T.M. and S.F and collected the data. T.M, C.T. and H.N. aided in interpreting the results and worked on the manuscript. H.N. supervised the project. S.T. wrote the manuscript with support from T.M. and C.T. All authors discussed the results and commented on the manuscript.

Corresponding author

Correspondence to Shinji Tanishima.

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Conflict of interests

There are no competing interests.

Ethics approval

The Ethics Committee of the Faculty of Medicine of Tottori University (approval No. 21A142).

Consent

We used the opt-out method to obtain consent from the patients to participate in this study. However, some patients died before the study. Hence, informed consent was not obtained. The Tottori University Ethics Committee has decided to exclude the data of the patients who died if the patients’ family refuses to provide consent based on the opt-out method. In fact, there were no cases waived by the families’ offer.

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Tanishima, S., Mihara, T., Takeda, C. et al. Trends in infectious spondylitis from 2000 to 2020. Eur Spine J (2024). https://doi.org/10.1007/s00586-024-08286-7

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