Abstract
Purpose
Studies about the clinical efficacy of endoscopic lumbar interbody fusion using an enhanced recovery after surgery (ERAS) pathway are insufficient. Thus, the purpose of this study was to investigate clinical usefulness of biportal endoscopic transforaminal lumbar interbody fusion (TLIF) using an ERAS compared with microscopic TLIF.
Methods
Prospectively collected data were retrospectively analyzed. Patients who received modified biportal endoscopic TLIF with ERAS were grouped into an endoscopic TLIF group. Those who received microscopic TLIF without ERAS were grouped into a microscopic TLIF group. Clinical and radiologic parameters were compared between two groups. Fusion rate was evaluated using sagittal reconstruction images of postoperative computed tomographic (CT) scan.
Results
There were 32 patients in the endoscopic TLIF group with ERAS and 41 patients in the microscopic TLIF group without ERAS. Visual analog scale (VAS) scores for back pain preoperatively at day one and day two were significantly (pā<ā0.05) higher in the non-ERAS microscopic TLIF group than in the ERAS endoscopic TLIF group. Preoperative Oswestry Disability Index were significantly improved at the last follow-up in both groups. The fusion rate at postoperative one year was 87.5% in the endoscopic TLIF group and 85.4% in the microscopic TLIF group.
Conclusion
Biportal endoscopic TLIF with ERAS pathway may have good aspect to accelerate recovery after surgery. There was no inferiority of fusion rate of endoscopic TLIF comparing to microscopic TLIF. Biportal endoscopic TLIF using a large cage with ERAS pathway may be a good alternative treatment for lumbar degenerative disease.
This is a preview of subscription content, access via your institution.





References
Fehlings MG, Tetreault L, Nater A, Choma T, Harrop J, Mroz T, Santaguida C, Smith JS (2015) The aging of the global population: the changing epidemiology of disease and spinal disorders. Neurosurgery 77(Suppl 4):S1-5. https://doi.org/10.1227/neu.0000000000000953
Debono B, Wainwright TW, Wang MY, Sigmundsson FG, Yang MMH, Smid-Nanninga H, Bonnal A, Le Huec JC, Fawcett WJ, Ljungqvist O, Lonjon G, de Boer HD (2021) Consensus statement for perioperative care in lumbar spinal fusion: enhanced recovery after surgery (ERASĀ®) society recommendations. Spine J 21:729ā752. https://doi.org/10.1016/j.spinee.2021.01.001
Heo DH, Park CK (2019) Clinical results of percutaneous biportal endoscopic lumbar interbody fusion with application of enhanced recovery after surgery. Neurosurg Focus 46:E18. https://doi.org/10.3171/2019.1.Focus18695
Heo DH, Ha JS, Jang JW (2023) Biportal endoscopic posterior cervical foraminotomy for adjacent 2-level foraminal lesions using a single approach (sliding technique). Neurospine 20:92ā98. https://doi.org/10.14245/ns.2346144.072
Heo DH, Eum JH, Jo JY, Chung H (2021) Modified far lateral endoscopic transforaminal lumbar interbody fusion using a biportal endoscopic approach: technical report and preliminary results. Acta Neurochir 163:1205ā1209. https://doi.org/10.1007/s00701-021-04758-7
Kang MS, Heo DH, Kim HB, Chung HT (2021) Biportal endoscopic technique for transforaminal lumbar interbody fusion: review of current research. Int J Spine Surg 15:S84-s92. https://doi.org/10.14444/8167
Park DY, Heo DH (2023) The use of dual direction expandable titanium cage with biportal endoscopic transforaminal lumbar interbody fusion: a technical consideration with preliminary results. Neurospine 20:110ā118. https://doi.org/10.14245/ns.2346116.058
Heo DH, Lee DC, Kim HS, Park CK, Chung H (2021) Clinical results and complications of endoscopic lumbar interbody fusion for lumbar degenerative disease: a meta-analysis. World Neurosurg 145:396ā404. https://doi.org/10.1016/j.wneu.2020.10.033
Lin GX, Yao ZK, Zhang X, Chen CM, Rui G, Hu BS (2022) Evaluation of the outcomes of biportal endoscopic lumbar interbody fusion compared with conventional fusion operations: a systematic review and meta-analysis. World Neurosurg 160:55ā66. https://doi.org/10.1016/j.wneu.2022.01.071
Soliman MAR, Aguirre AO, Kuo CC, Ruggiero N, Azmy S, Khan A, Ghannam MM, Almeida ND, Jowdy PK, Mullin JP, Pollina J (2022) Vertebral bone quality score independently predicts cage subsidence following transforaminal lumbar interbody fusion. Spine J 22:2017ā2023. https://doi.org/10.1016/j.spinee.2022.08.002
Sihvonen T, Herno A, PaljƤrvi L, Airaksinen O, Partanen J, Tapaninaho A (1993) Local denervation atrophy of paraspinal muscles in postoperative failed back syndrome. Spine 18:575ā581. https://doi.org/10.1097/00007632-199304000-00009
Kehlet H (1997) Multimodal approach to control postoperative pathophysiology and rehabilitation. Br J Anaesth 78:606ā617. https://doi.org/10.1093/bja/78.5.606
Sun Z, Qi Y (2022) Application of enhanced recovery after surgery care protocol in the perioperative care of patients undergoing lumbar fusion and internal fixation. J Orthop Surg Res 17:240. https://doi.org/10.1186/s13018-022-03099-0
Wang MY, Chang PY, Grossman J (2017) Development of an enhanced recovery after surgery (ERAS) approach for lumbar spinal fusion. J Neurosurg Spine 26:411ā418. https://doi.org/10.3171/2016.9.Spine16375
Band IC, Yenicay AO, Montemurno TD, Chan JS, Ogden AT (2022) Enhanced recovery after surgery protocol in minimally invasive lumbar fusion surgery reduces length of hospital stay and inpatient narcotic use. World Neurosurg X 14:100120. https://doi.org/10.1016/j.wnsx.2022.100120
Yang Y, Wu X, Wu W, Liu Z, Pang M, Chen Y, Ou Z, Rong L (2020) Enhanced recovery after surgery (ERAS) pathway for microendoscopy-assisted minimally invasive transforaminal lumbar interbody fusion. Clin Neurol Neurosurg 196:106003. https://doi.org/10.1016/j.clineuro.2020.106003
Tong Y, Fernandez L, Bendo JA, Spivak JM (2020) Enhanced recovery after surgery trends in adult spine surgery: a systematic review. Int J Spine Surg 14:623ā640. https://doi.org/10.14444/7083
Wang MY, Grossman J (2016) Endoscopic minimally invasive transforaminal interbody fusion without general anesthesia: initial clinical experience with 1-year follow-up. Neurosurg Focus 40:E13. https://doi.org/10.3171/2015.11.Focus15435
Lee SH, Erken HY, Bae J (2017) Percutaneous transforaminal endoscopic lumbar interbody fusion: clinical and radiological results of mean 46-month follow-up. Biomed Res Int 2017:3731983. https://doi.org/10.1155/2017/3731983
Morgenstern C, Yue JJ, Morgenstern R (2020) Full percutaneous transforaminal lumbar interbody fusion using the facet-sparing, trans-kambin approach. Clin Spine Surg 33:40ā45. https://doi.org/10.1097/bsd.0000000000000827
Hwa Eum J, Hwa Heo D, Son SK, Park CK (2016) Percutaneous biportal endoscopic decompression for lumbar spinal stenosis: a technical note and preliminary clinical results. J Neurosurg Spine 24:602ā607. https://doi.org/10.3171/2015.7.Spine15304
Heo DH, Son SK, Eum JH, Park CK (2017) Fully endoscopic lumbar interbody fusion using a percutaneous unilateral biportal endoscopic technique: technical note and preliminary clinical results. Neurosurg Focus 43:E8. https://doi.org/10.3171/2017.5.Focus17146
Choi KC, Shim HK, Hwang JS, Shin SH, Lee DC, Jung HH, Park HA, Park CK (2018) Comparison of surgical invasiveness between microdiscectomy and 3 different endoscopic discectomy techniques for lumbar disc herniation. World Neurosurg 116:e750āe758. https://doi.org/10.1016/j.wneu.2018.05.085
Jang JW, Lee DG, Park CK (2021) Rationale and advantages of endoscopic spine surgery. Int J Spine Surg 15:S11-s20. https://doi.org/10.14444/8160
Dietz N, Sharma M, Adams S, Alhourani A, Ugiliweneza B, Wang D, NuƱo M, Drazin D, Boakye M (2019) Enhanced recovery after surgery (ERAS) for Spine surgery: a systematic review. World Neurosurg 130:415ā426. https://doi.org/10.1016/j.wneu.2019.06.181
Zhang LK, Li Q, Quan RF, Liu JS (2021) Is preemptive analgesia a good choice for postoperative pain relief in lumbar spine surgeries?: A meta-analysis of randomized controlled trials. Medicine 100:e25319. https://doi.org/10.1097/md.0000000000025319
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors have no personal, financial, or institutional interest in any of the drugs, materials, or devices described in this article.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Heo, D.H., Jang, J.W. & Park, C.K. Enhanced recovery after surgery pathway with modified biportal endoscopic transforaminal lumbar interbody fusion using a large cage. Comparative study with minimally invasive microscopic transforaminal lumbar interbody fusion. Eur Spine J 32, 2853ā2862 (2023). https://doi.org/10.1007/s00586-023-07747-9
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00586-023-07747-9