Abstract
Study design
A systematic review and meta-analysis.
Objective
The purpose of this study was to evaluate the clinical outcome and safety of sacroplasty for patients with secondary metastatic lesions to the sacrum.
Methods
Several databases, including the Cochrane library, PubMed and EMBASE, were systematically searched to identify potentially eligible articles in English language. All the above databases were searched until December 2019. The search strategy was based on the combination of the following keywords: sacroplasty AND secondary tumours OR metastasis OR metastases. The reference list of the selected literature was also reviewed and a standard PRISMA template utilised.
Results
From a total of 102 articles initially identified, a final seven studies were identified as meeting the inclusion criteria. A total of 107 patients from these studies were included. The follow-up ranged from immediate post-operatively to 30.5 months. The mean preoperative VAS was 8.38 (range 6.9–9.3), which improved significantly to 3.01 (range 1.12–4.7) post-operatively (p < 0.001). The most frequent complication reported was cement leakage, which occurred in 26 patients (25.4%), but without any neurological or other adverse sequelae.
Conclusions
Sacroplasty in the management of secondary sacral tumours is a safe procedure that can achieve a significant reduction in pain, as quantified by VAS scores, and low complication rate.
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Tarawneh, A.M., Sabou, S., AlKalbani, S. et al. Clinical outcomes of sacroplasty for metastatic sacral tumours: a systematic review and meta-analysis. Eur Spine J 29, 3116–3122 (2020). https://doi.org/10.1007/s00586-020-06562-w
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DOI: https://doi.org/10.1007/s00586-020-06562-w