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Clinical outcomes and complication profile of total hip arthroplasty after lumbar spine fusion: a meta-analysis and systematic review

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Abstract

Background

Hip and spine pathology can alter the biomechanics of spino-pelvic mobility. Lumbar spine fusions can reduce the mobility of the lumbar spine and therefore result in compensatory femoral motion, contributing towards dislocations of THA.

Purpose

This meta-analysis aims to determine the effect of pre-existing spine fusions on THA outcomes, and complication profile including hip dislocations, all-cause revisions and all complications.

Methods

A multi-database search was performed according to PRISMA guidelines. All studies that compared patients who underwent THA with and without prior SF were included in the analysis.

Results

Ten studies were included in this review, consisting of 28,396 SF THA patients and 1,550,291 non-SF THA patients. There were statistically significant higher rates of hip dislocation (OR 2.20, 95% CI 1.71–2.85, p < 0.001), all-cause revision (OR 3.43, 95% CI 1.96–6.00, p < 0.001) and all complications (OR 2.83, 95% CI 1.28–6.24, p = 0.01) in SF than in non-SF THA patients. When registry data were excluded, these rates were approximately doubled. Subgroup analysis of revisions for dislocations was not statistically significant (OR 5.28, 95% CI 0.76–36.87, p = 0.09). While no meta-analysis was performed on clinical outcomes due to heterogeneous parameter reporting, individual studies reported significantly poorer outcomes in SF patients than in non-SF patients.

Conclusion

THA patients with SF are at higher risks of hip dislocations, all-cause revisions and all complications, which may adversely affect patient-reported outcomes. Surgeons should be aware of these risks and appropriately plan to account for altered spino-pelvic biomechanics, in order to reduce the risks of hip dislocations and other complications.

Level of evidence

II (Meta-analysis of non-homogeneous studies).

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, Box Hill Hospital, Box Hill, VIC, Australia

    James Randolph Onggo, Mithun Nambiar, Jason Derry Onggo, Anuruban Ambikaipalan, Sina Babazadeh & Raphael Hau

  2. Department of Surgery, The University of Melbourne, Parkville, VIC, Australia

    Mithun Nambiar

  3. School of Medicine, Flinders University, Adelaide, SA, Australia

    Jason Derry Onggo

  4. NeuroSpine Research Group, Sydney, NSW, Australia

    Kevin Phan

  5. Department of Orthopaedic Surgery, St Vincent’s Hospital, East Melbourne, VIC, Australia

    Sina Babazadeh

  6. Epworth Eastern Hospital, Box Hill, VIC, Australia

    Raphael Hau

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  1. James Randolph Onggo
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Contributions

JRO contributed to idea conception, literature search, data collection, statistics, manuscript writing and editing. MN contributed to idea conception, manuscript writing and editing. JO contributed to literature search, data collection, statistics, figures and tables, and manuscript writing. KP contributed to statistics, figures and manuscript writing. AA, SB and RH contributed to manuscript writing and editing.

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Correspondence to James Randolph Onggo.

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This work was primarily performed in Box Hill Hospital, Victoria, Australia.

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Onggo, J.R., Nambiar, M., Onggo, J.D. et al. Clinical outcomes and complication profile of total hip arthroplasty after lumbar spine fusion: a meta-analysis and systematic review. Eur Spine J 29, 282–294 (2020). https://doi.org/10.1007/s00586-019-06201-z

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