Prosthesis design influences segmental contribution to total cervical motion after cervical disc arthroplasty

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Abstract

Introduction

We investigated a new metric for assessing the quality of motion of the cervical segments over the arc of extension-to-flexion motion after cervical disc arthroplasty (CDA). We quantified: (1) the amount of motion contributed by individual spinal segments to the total cervical spine motion, termed segmental motion fraction, and its variation throughout the arc of extension-to-flexion motion and (2) how cervical disc arthroplasty using two distinct prosthesis designs may influence the segmental motion contributions.

Materials and methods

We tested 16 human C3–T1 spine specimens under physiologic loads; first intact, after CDA at C5–C6, and then at C5–C6 and C6–C7. The M6-C (Orthofix, USA) and Mobi-C (Zimmer, USA) disc prostheses were used in eight specimens each.

Results and conclusions

The designs of the cervical disc prostheses tested significantly influenced the variation in segmental motion fraction as the spine underwent motion between the endpoints of extension and flexion. While the mean segmental motion contribution to the total cervical motion was not influenced by prosthesis design, the way the motion took place between the extension and flexion endpoints was significantly influenced. The M6-C artificial disc restored physiologic motion quality such that implanted segments continued to function in harmony with other segments of the cervical spine as measured before arthroplasty. Conversely, the Mobi-C prosthesis, while maintaining average motion contributions similar to the pre-implantation values, demonstrated large deviations in motion contribution over the extension-to-flexion arc motion in ten of 16 implanted segments. Such non-physiologic implant kinematics could cause excessive prosthesis wear and motion and stress shielding at adjacent segments.

Graphic abstract

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Change history

  • 17 September 2020

    Unfortunately, figures 1 and 2 have been incorrectly published in the original publication. The complete correct figures are given below with the captions.

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Acknowledgements

This work was supported in part by research funding from the Department of Veterans Affairs and Chicago Association for Research and Education in Science, Hines, Illinois.

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Correspondence to Avinash G. Patwardhan.

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AG. Patwardhan is a consultant to Orthofix Inc., Lewisville TX, USA. RM. Havey has no conflict of interest.

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Patwardhan, A.G., Havey, R.M. Prosthesis design influences segmental contribution to total cervical motion after cervical disc arthroplasty. Eur Spine J (2019). https://doi.org/10.1007/s00586-019-06064-4

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Keywords

  • Cervical
  • Total disc replacement
  • Cervical disc arthroplasty
  • Quality of motion
  • Segmental motion fraction