European Spine Journal

, Volume 27, Issue 4, pp 882–890 | Cite as

Surgical complications of extraspinal tumors in the cervical spine: a report of 110 cases and literature review

  • WenHua Yang
  • Liang Jiang
  • XiaoGuang Liu
  • Feng Wei
  • Miao Yu
  • FengLiang Wu
  • Lei Dang
  • Hua Zhou
  • Hua Zhang
  • ZhongJun Liu
Original Article



To assess the safety of surgical intervention for extraspinal tumors in the cervical spine.


110 consecutive patients were enrolled and followed-up at least 12 months or until death. The complication rates and risk factors were documented and analyzed.


The quality of life in the surviving patients was significantly improved. The overall local recurrence rate was 17.3%. Twenty percent of patients developed distant metastasis. The perioperative mortality rate (30 days after surgery) was 0.9%. The complication related mortality was 1.8%. The rates of overall complication and major complication were 41.8% and 20.9%, respectively. The independent predictors for overall complications were Karnofsky score <60, multisegmental resection, and operation time >3 h. The independent predictors of major complications were comorbidity, tumor location at C1–C2, and combined approach.


Surgery for cervical spine tumor could improve the quality of life, though it might be accompanied with high morbidity and mortality. It is a highly demanding procedure; however, it can be performed to an acceptable degree of safety.


Spine tumor Cervical Surgery Complication Mortality 



The authors thank Ms ChenMei Ren for collecting the data.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.

Source of funding

The work described here was supported by the Research Grant of Peking University Third Hospital (No. Y71508-01).

Supplementary material

586_2017_5259_MOESM1_ESM.docx (56 kb)
Supplementary material 1 (DOCX 55 kb)


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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  1. 1.Orthopaedic DepartmentPeking University Third HospitalBeijingChina
  2. 2.Emergency Department, Beijing Shijitan HospitalCapital Medical UniversityBeijingChina
  3. 3.Research Center of Clinical EpidemiologyPeking University Third HospitalBeijingChina

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