Abstract
Purpose
This population-based cohort study investigated the association between a lifetime history of a low back injury in a motor vehicle collision (MVC) and future troublesome low back pain. Participants with a history of a low back injury in a motor vehicle collision who had recovered (no or mild low back pain) were compared to those without a history of injury. Current evidence from two cross-sectional and one prospective study suggests that individuals with a history of a low back injury in a MVC are more likely to experience future LBP. There is a need to test this association prospectively in population-based cohorts with adequate control of known confounders.
Methods
We formed a cohort of 789 randomly sampled Saskatchewan adults with no or mild LBP. At baseline, participants were asked if they had ever injured their low back in a MVC. Six and 12 months later, participants were asked about the presence of troublesome LBP (grade II–IV) on the Chronic Pain Grade Questionnaire. Multivariable Cox proportional hazards regression analysis was used to estimate the association while controlling for known confounders.
Results
The follow-up rate was 74.8% (590/789) at 6 months and 64.5% (509/789) at 12 months. There was a positive crude association between a history of low back injury in a MVC and the development of troublesome LBP over a 12-month period (HRR = 2.76; 95% CI 1.42–5.39). Controlling for arthritis reduced this association (HRR = 2.25; 95% CI 1.11–4.56). Adding confounders that may be on the casual pathway (baseline LBP, depression and HRQoL) to the multivariable model further reduced the association (HRR = 2.20; 95% CI 1.04–4.68).
Conclusion
Our analysis suggests that a history of low back injury in a MVC is a risk factor for developing future troublesome LBP. The consequences of a low back injury in a MVC can predispose individuals to experience recurrent episodes of low back pain.
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References
Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M et al (2012) Years lived with disability (YLD’s) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380:2163–2196
Murray CJL, Vos T, Lozano R, Naghavi M, Flaxman AD et al (2012) Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380:2197–2223
Hoy D, March L, Brooks P, Woolf A, Blyth F et al (2010) Measuring the global burden of low back pain. Best Pract Res Clin Rheumatol 24:155–165
Cassidy JD, Côté P, Carroll LJ, Kristman V (2005) Incidence and course of low back pain episodes in the general population. Spine 30(24):2817–2823
Hayden JA, Dunn KM, van der Windt DA, Shaw WS (2010) What is the prognosis of back pain? Best Pract Res Clin Rheumatol 24:167–179
Itz CJ, Geurts JW, van Kleef M, Nelemans P (2012) Clinical course of non-specific low back pain: a systematic review of prospective cohort studies set in primary care. Eur J Pain 17(1):5–15
Nolet PS, Kristman VL, Côté P, Carroll LJ, Hincapié C, Cassidy JD (2014) Is low back pain associated with worse health–related quality of life six month later? Eur Spine J 24(3):458–466
Hoy D, Bain C, Williams G, March L, Brooks P et al (2012) A systematic review of the global prevalence of low back pain. Arthritis Rheum 64(6):2028–2037
Bortsov AV, Platts-Mills TF, Peak DA, Jones JS, Swor RA et al (2014) Effect of pain location and duration on life function in the year after motor vehicle collision. Pain 155:1836–1845
Hincapié C, Cassidy JD, Carroll LJ, Côté P, Guzmán J (2010) Whiplash injury is more than neck pain: a population-study of pain localization after traffic injury. J Occup Environ Med 52(4):434–440
Cassidy JD, Carroll LJ, Côté P, Berglund A, Nygren Å (2003) Low back pain after traffic collisions: a population-based cohort study. Spine 28(10):1002–1009
Fujii T, Matsudaira K (2013) Prevalence of low back pain and factors associated with chronic disabling back pain in Japan. Eur Spine J 22:432–438
Myran R, Hagen K, Swebak S, Nygaard O, Zwart JA (2011) Headache and musculoskeletal complaints among subjects with self-reported whiplash injury: the HUNT-2 study. BMC Musculoskelet Disord 12:129
Berglund A, Alfredsson L, Jensen I, Cassidy JD, Nygren Å (2001) The association between exposure to a rear-end collision and future health complaints. J Clin Epidemiol 54:851–856
Nolet PS, Côté P, Cassidy JD, Carroll LJ (2011) The association between a lifetime history of a work-related neck injury and future neck pain: a population based cohort study. J Manip Physiol Ther 34(6):348–355
Carroll LJ, Cassidy JD, Côté P (2000) The Saskatchewan Health and Back Pain Survey: the prevalence and factors associated with depressive symptomatology in Saskatchewan adults. Can J Public Health 91:459–464
von Korff M, Ormel J, Keefe FJ, Dworkin SF (1992) Grading the severity of chronic pain. Pain 50:133–149
Ware JE Jr, Snow KK, Kosinski M et al (1993) SF-36 health survey: manual and interpretation guide. The Health Institute, New England Medical Center, Boston
Brazier JE, Harper R, Jones NM, O’Cathain A, Thomas KJ, Usherwood T, Westlake L (1992) Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ 305(6846):160–164
Beaton DC, Hogg-Johnson S, Bombardier C (1997) Evaluating changes in health status: reliability and responsiveness of five generic health status measures in workers with musculoskeletal disorders. J Clin Epidemiol 50(1):79–93
Ware JE, Gandek B (1998) Overview of the SF-36 health survey and the International Quality of Life Assessment (IQOLA) Project. J Clin Epidemiol 51(11):903–912
Ware JE (2000) SF-36 health survey update. Spine 25(24):3130–3139
Nolet PS, Côté P, Cassidy JD, Carroll LJ (2010) The association between a lifetime history of a neck injury in a motor vehicle collision and future neck pain: a population-based cohort study. Eur Spine J 19(6):972–981
Vermeulen S (2006) Assessing the performance of a self-report comorbidity scale. MSc Thesis, Unpublished manuscript, University of Alberta
Radloff LS (1997) The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas 1:385–401
Beekman AT, Deeg DJ, Van Limbeek J, Braam AW, De Vries MZ, Tilburg W (1997) Criterion Validity of the Center for Epidemiologic Studies Depression Scale (CES-D): results from a community-based sample of older participants in The Netherlands. Psychol Med 27(1):231–235
Boyd JH, Weissman MM, Thompson WD, Myers JK (1982) Screening for depression in a community sample. Arch Gen Psychiatry 39(10):1195–2000
Devins GM, Orme CM, Costello CG, Minik YM, Frizzell B, Stam HJ, Pullin WM (1988) Measuring depressive symptoms in illness populations: psychiatric properties of the Center for Epidemiological Studies Depression (CES-D) Scale. Psychol Health 2:139–156
Rothman KJ (2002) Epidemiology, an introduction. Oxford University Press, New York
IBM Corp (2013) Released IBM SPSS Statistics for Windows, Version 22.0. IBM Corp, Armonk
Nolet PS, Kristman VL, Côté P, Carroll LJ, Hincapié Cassidy JD (2016) The association between a lifetime history of work-related low back injury and future low back pain: a population-based cohort study. Eur Spine J 25(4):1242–1250
Schisterman EF, Cole SR, Platt RW (2009) Overadjustment bias and unnecessary adjustment in epidemiologic studies. Epidemiology 20:488–495
Begg KJ, Langley JD, Williams SM (1999) Validity of self reported crashes and injuries in a longitudinal study of young adults. Injury Prev 5:142–144
Pons-Villanueva J, Gegui-Gomez M (2010) Validation of self-reported motor vehicle crash and related work leave in a multi-purpose prospective cohort. Int J Inj Control Saf Promot 17(4):223–230
Cassidy JD, Carroll LJ, Côté P (1998) The Saskatchewan Health and Back Pain Survey, the prevalence of low back pain and related disability in Saskatchewan adults. Spine 23(17):1860–1867
Acknowledgments
The authors would like to acknowledge the Chiropractors’ Association of Saskatchewan for funding the Saskatchewan Health and Back Pain Survey and the assistance of Saskatchewan Health in sampling the Saskatchewan population. Dr. Kristman is supported by the Canadian Institutes of Health Research through a New Investigator Award in Community-based Primary Health Care.
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Nolet, P.S., Kristman, V.L., Côté, P. et al. The association between a lifetime history of low back injury in a motor vehicle collision and future low back pain: a population-based cohort study. Eur Spine J 27, 136–144 (2018). https://doi.org/10.1007/s00586-017-5090-y
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DOI: https://doi.org/10.1007/s00586-017-5090-y
Keywords
- Low back pain
- Traffic accidents
- Whiplash injuries
- Risk factors
- Cohort studies