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Aggressive osteoblastoma of the cervical spine involving the canal and vertebral artery: a case report

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Abstract

Objective

We present such a case of aggressive osteoblastoma of cervical spine. We describe its complicated clinical progression, hoping to shed light on the surgical strategy of this complex tumor.

Methods

We present such a case of aggressive osteoblastoma involving the C6–7 vertebrae. A 25-year-old man was diagnosed as aggressive osteoblastoma of the cervical spine. The lesion encroached upon the radicular foramina and was located adjacent to the canal of the vertebral artery. Preoperative embolization was performed to reduce intraoperative bleeding and to prevent intraoperative injury of the vertebral artery.

Results

A pathologic examination showed osteoblasts suggestive of osteoblastoma. At 2-year follow-up, bony union was achieved, and there was no evidence of recurrence on a CT scan.

Conclusion

En bloc total resection for highly vascular osteoblastoma is ideal, but this case shows that piecemeal total resection following preoperative embolization is a surgical option for highly expansive osteoblastoma.

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References

  1. Japanese Orthopaedic Association (1994) Scoring system for cervical myelopathy. J Jpn Orthop Assoc 68:134–147

    Google Scholar 

  2. Arkader A, Dormans JP (2008) Osteoblastoma in the skeletally immature. J Pediatr Orthop 28:555–560

    Article  PubMed  Google Scholar 

  3. Azouz EM, Kozlowski K, Marton D, Sprague P, Zerhouni A, Asselah F (1986) Osteoid osteoma and osteoblastoma of the spine in children. Report of 22 cases with brief literature review. Pediatr Radiol 16:25–31

    Article  CAS  PubMed  Google Scholar 

  4. Baysefer A, Akay KM, Izci Y, Kayali H, Timurkaynak E (2004) The clinical and surgical aspects of spinal tumors in children. Pediatr Neurol 31:261–266

    Article  PubMed  Google Scholar 

  5. Boriani S, Amendola L, Bandiera S, Simoes CE, Alberghini M, Di Fiore M et al (2012) Staging and treatment of osteoblastoma in the mobile spine: a review of 51 cases. Eur Spine J 21:2003–2010

    Article  PubMed  PubMed Central  Google Scholar 

  6. Burn SC, Ansorge O, Zeller R, Drake JM (2009) Management of osteoblastoma and osteoid osteoma of the spine in childhood. J Neurosurg Pediatr 4:434–438

    Article  PubMed  Google Scholar 

  7. Combalia Aleu A, Popescu D, Pomes J, Palacin A (2008) Long-standing pain in a 25-year-old patient with a non-diagnosed cervical osteoblastoma: a case report. Arch Orthop Trauma Surg 128:567–571

    Article  CAS  PubMed  Google Scholar 

  8. Dick HM, Bigliani LU, Michelsen WJ, Johnston AD, Stinchfield FE (1979) Adjuvant arterial embolization in the treatment of benign primary bone tumors in children. Clin Orthop Relat Res 139:133–141

    Google Scholar 

  9. Dorfman HD, Weiss SW (1984) Borderline osteoblastic tumors: problems in the differential diagnosis of aggressive osteoblastoma and low-grade osteosarcoma. Semin Diagn Pathol 1:215–234

    CAS  PubMed  Google Scholar 

  10. Enneking WF (1986) A system of staging musculoskeletal neoplasms. Clin Orthop Relat Res 204:9–24

    Google Scholar 

  11. Feng G, Huang K, Li L, Gong Q, Liu H, Song Y (2014) Treatment of osteoblastoma at C3-4 in a child: a case report. BMC Musculoskelet Disord 15:313

    Article  PubMed  PubMed Central  Google Scholar 

  12. Greenspan A (1993) Benign bone-forming lesions: osteoma, osteoid osteoma, and osteoblastoma. Clinical, imaging, pathologic, and differential considerations. Skeletal Radiol 22:485–500

    CAS  PubMed  Google Scholar 

  13. Haghnegahdar A, Sedighi M (2016) Anterior Reconstruction of C2-C3 Bodies in a 6-Year-Old Patient with a Huge Osteoblastoma: A Novel Technique. Global Spine J 6:e21–e29

    Article  PubMed  Google Scholar 

  14. Harrop JS, Schmidt MH, Boriani S, Shaffrey CI (2009) Aggressive “benign” primary spine neoplasms: osteoblastoma, aneurysmal bone cyst, and giant cell tumor. Spine (Phila Pa 1976) 34:S39–47

    Article  Google Scholar 

  15. Jaffe HL (1956) Benign osteoblastoma. Bull Hosp Joint Dis 17:141–151

    CAS  PubMed  Google Scholar 

  16. Jiang L, Liu XG, Wang C, Yang SM, Liu C, Wei F et al (2015) Surgical treatment options for aggressive osteoblastoma in the mobile spine. Eur Spine J 24:1778–1785

    Article  PubMed  Google Scholar 

  17. Lichtenstein L (1956) Benign osteoblastoma; a category of osteoid-and bone-forming tumors other than classical osteoid osteoma, which may be mistaken for giant-cell tumor or osteogenic sarcoma. Cancer 9:1044–1052

    Article  CAS  PubMed  Google Scholar 

  18. Lucas DR, Unni KK, McLeod RA, O’Connor MI, Sim FH (1994) Osteoblastoma: clinicopathologic study of 306 cases. Hum Pathol 25:117–134

    Article  CAS  PubMed  Google Scholar 

  19. Marsh BW, Bonfiglio M, Brady LP, Enneking WF (1975) Benign osteoblastoma: range of manifestations. J Bone Joint Surg Am 57:1–9

    Article  CAS  PubMed  Google Scholar 

  20. Pochaczevsky R, Yen YM, Sherman RS (1960) The roentgen appearance of benign osteoblastoma. Radiology 75:429–437

    Article  CAS  PubMed  Google Scholar 

  21. Raskas DS, Graziano GP, Herzenberg JE, Heidelberger KP, Hensinger RN (1992) Osteoid osteoma and osteoblastoma of the spine. J Spinal Disord 5:204–211

    Article  CAS  PubMed  Google Scholar 

  22. Saccomanni B (2009) Osteoid osteoma and osteoblastoma of the spine: a review of the literature. Curr Rev Musculoskelet Med 2:65–67

    Article  PubMed  PubMed Central  Google Scholar 

  23. Saglik Y, Atalar H, Yildiz Y, Basarir K, Gunay C (2007) Surgical treatment of osteoblastoma: a report of 20 cases. Acta Orthop Belg 73:747–753

    PubMed  Google Scholar 

  24. Silva ML, Brunelle F (1996) Embolisation of vascular lesions of the spinal column in childhood: a report of three cases. Neuroradiology 38:809–811

    Article  CAS  PubMed  Google Scholar 

  25. Stavridis SI, Pingel A, Schnake KJ, Kandziora F (2013) Diagnosis and treatment of a C2-osteoblastoma encompassing the vertebral artery. Eur Spine J 22:2504–2512

    Article  PubMed  PubMed Central  Google Scholar 

  26. Trubenbach J, Nagele T, Bauer T, Ernemann U (2006) Preoperative embolization of cervical spine osteoblastomas: report of three cases. AJNR Am J Neuroradiol 27:1910–1912

    CAS  PubMed  Google Scholar 

  27. Uccello M, Vacante M, Giordano M, Malaguarnera M, Biondi A, Basile F et al (2012) Osteoblastoma of cervical spine causing an unusual neck pain. Eur Rev Med Pharmacol Sci 16(Suppl 4):17–20

    PubMed  Google Scholar 

  28. Wozniak AW, Nowaczyk MT, Osmola K, Golusinski W (2010) Malignant transformation of an osteoblastoma of the mandible: case report and review of the literature. Eur Arch Otorhinolaryngol 267:845–849

    Article  PubMed  Google Scholar 

  29. Zileli M, Cagli S, Basdemir G, Ersahin Y (2003) Osteoid osteomas and osteoblastomas of the spine. Neurosurg Focus 15:E5

    PubMed  Google Scholar 

  30. Zileli M, Kilincer C, Ersahin Y, Cagli S (2007) Primary tumors of the cervical spine: a retrospective review of 35 surgically managed cases. Spine J 7:165–173

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Showa-ward, Nagoya, Aichi, 466-8550, Japan

    Kei Ando, Shiro Imagama, Kazuyoshi Kobayashi, Yoshihiro Nishida & Naoki Ishiguro

Authors
  1. Kei Ando
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  2. Shiro Imagama
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  3. Kazuyoshi Kobayashi
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  4. Yoshihiro Nishida
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  5. Naoki Ishiguro
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Corresponding author

Correspondence to Shiro Imagama.

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None of the authors has any potential conflict of interest.

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Ando, K., Imagama, S., Kobayashi, K. et al. Aggressive osteoblastoma of the cervical spine involving the canal and vertebral artery: a case report. Eur Spine J 26 (Suppl 1), 111–116 (2017). https://doi.org/10.1007/s00586-016-4904-7

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  • DOI: https://doi.org/10.1007/s00586-016-4904-7

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