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Evaluation of autologous platelet concentrate for intertransverse lumbar fusion

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Abstract

Introduction

The aim of the study was to analyze if the adding of autologous platelet concentrate (APC) to a mixture of local autograft plus tricalcium phosphate and hidroxiapatite (TCP/HA) would improve the fusion rate in posterolateral lumbar fusion.

Materials and methods

A prospective, controlled, blinded, non-randomized clinical trial was carried out in 107 patients affected by degenerative lumbar pathology. The study group consisted of 67 patients, in which autologous platelet concentration was added to a mixture of autologous local bone graft and TCP/HA. A control group of 40 patients with same pathology and surgical technique but without APC addition was used to compare the fusion mass obtained. By means of plain X-rays, a blinded evaluation of the intertransverse fusion mass quality at twelve and twenty-four months was made according to type A (bilateral uniform mass), type B (unilateral uniform mass) and type C (irregular or lack bilateral mass). Patients with type C were regarded as pseudoarthrosis.

Results

In the study group 17 patients had lack or irregular fusion mass (25.4%) versus three patients in the control group (7.5%), which was statistically significant.

Conclusions

This study shows that the adding of autologous platelet concentration to a mixture of autologous bone graft plus TCP/HA has decreased our rates of posterolateral lumbar fusion.

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Conflict of interest

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Authors and Affiliations

  1. Spine Unit, Orthopaedic Surgery and Trauma Department, Cabueñes Hospital, Gijon, Asturias, Spain

    Gonzalo Acebal-Cortina, Miguel A. Suárez-Suárez, Constantino García-Menéndez, Luis Moro-Barrero, Roberto Iglesias-Colao & Ana Torres-Pérez

  2. Facultad de Medicina y Ciencias de la Salud, Oviedo University, Asturias, Spain

    Miguel A. Suárez-Suárez

  3. 276, Camino de las Begonias, 33203, Gijon, Spain

    Gonzalo Acebal-Cortina

Authors
  1. Gonzalo Acebal-Cortina
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  2. Miguel A. Suárez-Suárez
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  3. Constantino García-Menéndez
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  4. Luis Moro-Barrero
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  5. Roberto Iglesias-Colao
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  6. Ana Torres-Pérez
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Correspondence to Gonzalo Acebal-Cortina.

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Acebal-Cortina, G., Suárez-Suárez, M.A., García-Menéndez, C. et al. Evaluation of autologous platelet concentrate for intertransverse lumbar fusion. Eur Spine J 20 (Suppl 3), 361 (2011). https://doi.org/10.1007/s00586-011-1904-5

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  • DOI: https://doi.org/10.1007/s00586-011-1904-5

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