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Does scoliosis causes low bone mass? A comparative study between siblings

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Abstract

The aim of this study is to assess the prevalence low bone mass among girls with adolescent idiopathic scoliosis (AIS) and their siblings. The subjects of this study were Saudi Arabian girls with AIS. Patients had their weight and height measured to calculate their body mass index (BMI). Clinical examination and investigations were done to rule out any other cause of scoliosis. All had bone mineral density (BMD) measurement of hip area and the spine using DEXA scan, Hologic Inc. Patients with a BMD of < −2.6 was taken as osteoporotic and those between < −1 and −2.5 was taken as osteopenic for analysis. As control subjects, siblings of the patients with normal spine had their BMI calculated and BMD measurement done. We were able to analyze the data of 32 girls with an average age of 18.42 ± 5.71 (14–26) years with mean BMI of 17.7 ± 0.69 (16.5–18.5) kg/M2. Analysis of the scans of the hip revealed that 62.5% of the patients were osteoporotic with BMD of 0.837 (0.697–0.936) ± 0.04, T-score −3.8 ± 0.56 (−2.6 to −3.9) and Z-score. Nine (28.1%) were osteopenic with BMD of 0.768 ± 0.15 (0.638–0.878), mean T-score of −1.6 (−1.1 to 2.5) and Z-score −3.5 ± 0.63 (−2.9 to −3.9). Analysis of BMD of the spine showed similar results. In comparison to the scoliotics, girls with normal spine had higher BMI and BMD which was statistically significant at P < 0.001. T- and Z-score was also lower in scoliotic girls in comparison with girls with normal spine significant at P < 0.001 (CI 95%). Our study indicates that the scoliosis causes osteopenia and osteoporosis among girls while their siblings with normal spine remain with normal bone mass.

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References

  1. Ardawi MSM, Maimany AA, Bahksh TM, Nasrat HAN, Milaat WA, Al-Raddadi RM (2005) Bone mineral density of the spine and femur in healthy Saudis. Osteop Int 16:43–55

    Article  Google Scholar 

  2. Burner WL, Badger VM, Sherman FC (1982) Osteoporosis and acquired back deformities. J Pediatr Orthop 2:383–385

    PubMed  Google Scholar 

  3. Cheng JC, Qin L, Cheung CS, Sher AH, Lee KM, Ng SW, Guo X (2000) Generalized low areal and volumetric bone mineral density in adolescent idiopathic scoliosis. J Bone Miner Res 15:1587–1595

    Article  PubMed  CAS  Google Scholar 

  4. Cheung CSK, Lee WTK, Tse YK, Lee KM, Guo X, Qin L et al (2006) Generalized osteopenia in adolescent idiopathic scoliosis-association with abnormal pubertal growth, bone turnover, and calcium intake. Spine 31:330–338

    Article  PubMed  Google Scholar 

  5. Chung JCY, Guo X (1997) Osteopenia in adolescent idiopathic scoliosis—a primary problem or secondary to the spinal deformity? Spine 22:1716–1721

    Article  Google Scholar 

  6. Cook SD, Harding AF, Morgan EL, Nicholson RJ, Thomas KA, Whitecloud TS, Ratner ES (1987) Trabecular bone mineral density in idiopathic scoliosis. J Pediatr Orthop 7:168–174

    PubMed  CAS  Google Scholar 

  7. Corea JR, Maqbool G, Al-Arfaj AL, Sankaran-Kutty M (1987) Screening for musculoskeletal deformitiesin school children. KASCT Project Final Report; p 17

  8. El-Desouki M (2003) Osteoporosis in postmenopausal Saudi women using dual X-ray bone densitometry. Saudi Med J24:953–956

    Google Scholar 

  9. Giannoudis P, Tzioupis C, Almalki T, Buckley R (2007) Fracture healing in osteoporotic fractures: is it really different? A basic science perspective. Injury 38(Suppl 1):S90–S99

    Article  PubMed  Google Scholar 

  10. Hung VWY, Cheung CSK, Lam TP, Ng BKW, Tse YK, Guo X et al. (2005) Osteopenia: a new prognostic factor of curve progression in Adolescent Idiopathic Scoliosis. J Bone Joint Surg 87-A(12):2709–2716

    Google Scholar 

  11. Lee WTK (2005) Generalized low bone of girls with adolescent idiopathic scoliosis is related to inadequate calcium intake and weight bearing physical activity in prepubertal period. Osteoporosis Int 16:1024–1035

    Article  CAS  Google Scholar 

  12. Lonstein JE, Carlson JM (1984) The prediction of curve progression in untreated idiopathic scoliosis during growth. J Bone Joint Surg 66-A:1061–1071

    Google Scholar 

  13. McCann RM, Colleary G, Geddis C, Clarke SA, Jordan GR, Dickson GR, Marsh D (2007) Effect of osteoporosis on bone mineral density and fracture repair in a rat femoral fracture model. J Orthop Res (Epub ahead of print)

  14. Miller NH (1999) Cause and natural history of adolescent idiopathic scoliosis Ortho Clin N Am 30:343–352

    CAS  Google Scholar 

  15. Peterson LE, Nachemson AL (1995) Prediction of progression of the curve in girls who have adolescent idiopathic scoliosis of moderate. Logistic regression analysis based on data from the Brace Study of the Scoliosis Research Society. J Bone and Joint Surg 77:823–827

    CAS  Google Scholar 

  16. Roach JW (1999) Adolscent idiopathic scoliosis. Ortho Clin N Am 30:353–365

    Article  CAS  Google Scholar 

  17. Sadat-Ali M (1998) School screening for scoliosis. Have we done enough. Saudi Med J 19(2):210–211

    Google Scholar 

  18. Sadat-Ali M, Al-Habdan I, Fatma Al-Mulhim, Yousef A (2004) Bone mineral density among postmenopausal Saudi Arabian women. Saudi Med J 25(11):1623–1625

    PubMed  Google Scholar 

  19. Sadat-Ali M, Al-Habdan I, Al-Mulhim AA, Yousef A (2005) Effect of parity on bonemineral density in postmenopausal Saudi women. Saudi Med J 26(10):1588–1590

    PubMed  Google Scholar 

  20. Sadat-Ali M, El-Hassan AY, Ezzeldin IM, Al-Frehi H, Al-Mohanna F (1993) Postmenopausal osteoporosis in Saudi women: a pilot screening. Ann Saudi Med 13:272–274

    PubMed  CAS  Google Scholar 

  21. Sadat-Ali M, Al-Habdan I, Marwah S (1996) Bone mineral density measurements of distal radius in Saudi Arabian females. Ann Saudi Med 16(4):414–416

    PubMed  CAS  Google Scholar 

  22. Thomas KA, Cook SD, Skalley TC (1992) Lumbar spine and femoral mineral density in idiopathic scoliosis. A follow up study. J Pediatr Orthop 12:235–240

    CAS  Google Scholar 

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Correspondence to Mir Sadat-Ali.

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Sadat-Ali, M., Al-Othman, A., Bubshait, D. et al. Does scoliosis causes low bone mass? A comparative study between siblings. Eur Spine J 17, 944–947 (2008). https://doi.org/10.1007/s00586-008-0671-4

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  • DOI: https://doi.org/10.1007/s00586-008-0671-4

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