Diagnosis and treatment of canine leptospirosis due to serovar Bataviae—a case report

Abstract

Infection of Leptospira interrogans var. Bataviae in a properly vaccinated German shepherd dog and its successful clinical management are described. The dog was presented with a history of anorexia, vomiting, oliguria, melena, lethargy, and weakness. The animal had a proper history of yearly vaccination with the multicomponent vaccine. Hematology revealed leucocytosis, thrombocytopenia, granulocytosis, and anemia. Serum biochemical analysis showed elevated BUN, creatinine, ALP, total bilirubin, hypoalbuminemia, hyperglobulinemia, and lower A:G ratio. Based upon the clinical signs and blood-biochemical changes, the case was tentatively diagnosed as leptospirosis. Confirmation was done by microscopic agglutination test (MAT) along with polymerase chain reaction (PCR). The dog was treated with benzylpenicillin at a dose rate of 40,000 units/kg body weight intravenously twice a day along with proton pump inhibitors, fluids, electrolytes, and vitamin supplements for 5 days. The animal made a considerable improvement in condition after 5 days of treatment. To prevent persistent renal shedding of Leptospira organism, the animal was treated with doxycycline orally for 14 days. The animal made a complete recovery after 3 weeks of care. This case reports the emergence of a new Leptospira serovar in dogs of Kerala characterized by hepatic, renal, and hemorrhagic clinical manifestations. This case points towards the need for a seroprevalence study of leptospirosis in canines followed by incorporation of emerging serovars into the vaccination regime.

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Correspondence to Khan Sharun.

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This article does not contain any studies with human or animal participants performed by any of the authors. The article reports a clinical case presented at the University Veterinary Hospital (UVH), Kokkalai, Thrissur, Kerala. All protocols followed were as per the guidelines from the standard textbooks in Veterinary Medicine and were ethical.

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Sharun, K., Anjana, S., Dhivahar, M. et al. Diagnosis and treatment of canine leptospirosis due to serovar Bataviae—a case report. Comp Clin Pathol 28, 1829–1833 (2019). https://doi.org/10.1007/s00580-019-02949-4

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Keywords

  • Leptospirosis
  • Bataviae
  • Emerging serovars
  • Microscopic agglutination test