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Erysipelas, the opportunistic zoonotic disease: history, epidemiology, pathology, and diagnosis—a review

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Abstract

Due to the recent multidisciplinary collaborations towards ‘One Health’, it was necessary to review this important zoonotic disease, erysipelas. Swine erysipelas also referred to as diamond skin disease has since become one of the most serious hazards of swine production worldwide. Erysipelothrix rhusiopathiae, the aetiology of erysipelas could affect pigs, turkeys, sheep, chickens, ducks, and emus. The most important animal reservoir of E. rhusiopathiae is the domestic swine. The organism is shed by diseased animals in faeces, urine, saliva, and nasal secretions, which can contaminate food, water, and soil. Swine erysipelas is made up of the hyperacute form, the septicaemia, and cutaneous (diamond) forms (acute), and the chronic form, characterised in pigs by joint lesions (arthritis), vegetative endocarditis, alopecia, and dermatitis. These signs are accompanied by poor fertility, increased prevalence of abortions, stillbirths, and small litter size. Reports of human cases are related to occupational exposure placing fishermen, butchers, slaughterhouse workers, veterinarians, housewives, poultry industry workers, and other agricultural based workers at higher risk. Diagnosis of erysipelas is based on clinical signs, gross lesions, response to antimicrobial therapy, and demonstration of the bacterium using bacterial culturing, mouse protection test, microscopy and mass spectrometry or demonstration of bacterial DNA in tissues from affected animals using PCR assays, immunohistochemical methods, and other serological methods. Swine erysipelas as an opportunistic zoonotic disease is on the increase hence, a synergistic effort should be garnered towards reducing the negative influence of this disease, through enhanced awareness of this disease amongst farmers, butchers, housewives, veterinarians, and drug researchers.

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Acknowledgements

Special appreciation goes to Prof A.K.B Sackey of the Department of Veterinary Medicine, Ahmadu Bello University Zaria, who helped proofread this manuscript.

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Authors and Affiliations

  1. Department of Veterinary Pathology and Microbiology, University of Nigeria, Nsukka, Nigeria

    Iniobong C. I. Ugochukwu

  2. National Animal Production Research Institute, Ahmadu Bello University, Zaria, Nigeria

    Felix Samuel

  3. Department of Veterinary Pathology, Ahmadu Bello University, Zaria, Nigeria

    Ochuko Orakpoghenor

  4. Department of Veterinary Public Health and Preventive Medicine, University of Nigeria, Nsukka, Nigeria

    Obichukwu C. Nwobi, Chidiebere O. Anyaoha & Lynda O. Majesty-Alukagberie

  5. University Medical Centre, University of Nigeria, Nsukka, Nigeria

    Miracle O. Ugochukwu

  6. Department of Veterinary Medicine, University of Nigeria, Nsukka, Nigeria

    Emmanuel Ikenna Ugochukwu

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  1. Iniobong C. I. Ugochukwu
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Ugochukwu, I.C.I., Samuel, F., Orakpoghenor, O. et al. Erysipelas, the opportunistic zoonotic disease: history, epidemiology, pathology, and diagnosis—a review. Comp Clin Pathol 28, 853–859 (2019). https://doi.org/10.1007/s00580-018-2856-5

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