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Antibiotic resistance profile of Trueperella pyogenes isolated from three cases of goat kids affected by sever cardiopulmonary disease

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Abstract

Three 20-day-old female Cashmere (Raini) goat kids were presented in a sternal recumbency status with 3 weeks history of bilateral mucopurulent nasal discharge, anorexia, lethargy, and jugular distention hemato-biochemical profile showed leukocytosis (monocytosis, neutrophilia with bandemia) and a significant increase (p < 0.05) in the serum concentrations of total protein and fibrinogen. The goats died 1 week after treatment because of the severity of the disease. At necropsy, multiple pyogenic abscesses in the liver, myocardial abscesses, and fibrous pleural adhesions were observed. Histopathological examination revealed supportive hepatitis, formation of granulation tissue in the epicardial and myocardial layer of the heart and chronic suppurative bronchopneumonia with granulation tissue in the pleura. In bacteriological examination, Trueperella pyogenes (T. pyogenes) was isolated from the abscess and confirmed by PCR. The isolated bacteria showed the most susceptibility to the cefotaxime and the less susceptibility to oxytetracycline and gentamycin. Overall, this is the first report, which offered this bacterium as a causative agent of the wide ranges of pathological conditions in Cashmere goats. Suitable antimicrobial therapy of which the Clinician should be aware.

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Funding

This work was supported financially by a Grant number MP/342/41 for Scientific Research from Vice Chancellor of Research of Shahid Bahonar University of Kerman, Kerman, Iran.

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Authors and Affiliations

  1. Department of Pathobiology, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, 7616914111, Iran

    Nasrin Askari, Reza Kheirandish, Saeed Hasanzadeh, Majid Hemati, Sanaz Dehdashti & Farnoosh Bakhshaei

  2. Department of Clinical Science, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran

    Amir Saeed Samimi

  3. Molecular Microbiology Research Group, Shahid Bahonar University of Kerman, Kerman, Iran

    Reza Ghanbarpour

Authors
  1. Nasrin Askari
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  2. Amir Saeed Samimi
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  3. Reza Kheirandish
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  4. Reza Ghanbarpour
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  5. Saeed Hasanzadeh
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  6. Majid Hemati
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  7. Sanaz Dehdashti
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  8. Farnoosh Bakhshaei
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Correspondence to Nasrin Askari.

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The authors declare that they have no competing interests.

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All the applicable international, national, and/or institutional guidelines for the care and use of animals were followed in this study.

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Askari, N., Samimi, A.S., Kheirandish, R. et al. Antibiotic resistance profile of Trueperella pyogenes isolated from three cases of goat kids affected by sever cardiopulmonary disease. Comp Clin Pathol 27, 1107–1111 (2018). https://doi.org/10.1007/s00580-018-2760-z

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  • DOI: https://doi.org/10.1007/s00580-018-2760-z

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