Skip to main content

Advertisement

SpringerLink
Log in

Mammary gland carcinoma “in situ” in a male dog: case report

  • Case Report
  • Published:
Comparative Clinical Pathology Aims and scope Submit manuscript

Abstract

Mammary gland tumors are among the most frequently diagnosed neoplasms in female dogs. However, they are rare in male dogs, with incidence ranging from 0 to 2.7% (less than 1% on average). The triggering factors in males are still obscure, but studies have shown that hormonal abnormalities, especially those associated with testicular neoplasms, predispose towards their occurrence. Among the most common histological types diagnosed in males, adenocarcinoma, papillary cystadenocarcinoma, carcinosarcoma, simple adenoma, and spindle cell sarcoma can be highlighted. However, there are no reports of carcinoma “in situ” in males and its incidence in females is low. The present study reports a case of carcinoma in situ in a 13-year-old mixed-breed male dog, comprising a mammary gland tumor associated with mastitis, together with two histologically distinct tumors in the testicles (one in each): one was a diffuse seminoma and the other, a solid interstitial cell tumor. The present report is novel because of the histology of the mammary gland tumor.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  • Bearss JJ, Schulman FY, Carter D (2012) Histologic, immuno-histochemical and clinical features of 27 mammary tumours in 18 male dogs. Vet Pathol 49:602–607. https://doi.org/10.1177/0300985811402843

    Article  PubMed  CAS  Google Scholar 

  • Bettini CM, Anami RM, Assis MMQ, Monteiro ER, Headley SA (2006) Alopecia e características fenotípicas de feminização associado a tumor de células de leydigem um cão. Rev Acad 4(4):25–32 http://www2.pucpr.br/reol/pb/index.php/academica?dd1=1028&dd99=view&dd98=pb. Accessed 29 april 2017

    Google Scholar 

  • Biondi LR, Gentile LB, Rego AAMS, Noronha NP, Dagli MLZ (2014) Canine mammary tumors in Santos, Brazil: clinicopathological and survival profile. Braz J Vet Res Anim Sci 51(3):252–262. https://doi.org/10.11606/issn.1678-4456.v51i3p252-262

    Article  Google Scholar 

  • Brodey RS, Goldschmidt MH, Roszel JR (1983) Canine mammary gland neoplasms. J Am Anim Hosp Assoc 19:61-89

  • Costa MM (2010) Estudo Epidemiológico e anatomo-patológico de tumors mamários na cadela e na gata. Dissertation, Universidade Técnica de Lisboa, Lisboa

  • Filho JCO, Kommers GD, Masuda KE, Marques BMFPP, Fighera RA, Irigoyen LF, Barros CSL (2010) Estudo retrospectivo de 1.647 tumores mamários em cães. Pesqui Vet Bras 30(2):177–185. https://doi.org/10.1590/S0100-736X2010000200014

    Article  Google Scholar 

  • Goldschmidt M, Penã LR, Zappulli V (2011) Classification and grading of canine mammary tumors. Vet Pathol 48:117–131. https://doi.org/10.1177/0300985810393258

    Article  PubMed  CAS  Google Scholar 

  • Gupta K, Sood NK, Uppal SK, Jr M, Mahajan S, Raghunath M, Kiranjeet S (2012) Epidemiological studies on canine mammary tumour and its relevance for breast cancer studies. IOSR J Pharm 2:322–333. https://doi.org/10.9790/3013-0220322333

    Article  Google Scholar 

  • Maiti S, Kumar DKM, Kumar S, Ravindran NA, Mathew D, Palakkara S, Muthalavi MA, Kumar N (2014) Mammary gland tumours in male dogs: a hormonal and tumour marker study. Veterinarski Arhiv 84(5):537–548 http://hrcak.srce.hr/128662

    Google Scholar 

  • Misdorp, W (2002) Tumors of the mammary gland. In: Meuten, DJ Meuten (Ed.), Tumors in domestic animals, 4rd ed. Iowa: Iowa State Press, pp. 575-606

  • Peleteiro, MC (1994) Tumores mamários na cadela e na gata. Revista Portuguesa de Ciências Veterinárias 89:10-28

  • Peleteiro C, Branco S, Correia J (1996) Estudo epidemiológico de tumores mamários em cadela. In C. Peleteiro, S. Branco & J.Correia, Libro de Actas-VIII Reunion Sociedad Española de Anatomia Patológica Veterinária (SEAPV). Córdoba, Espanha p.66

  • Peters MAJ, Rooij DG, Teerds KJ, Gaag I, Sluijs FJ (2000) Spermatogenesis and testicular tumours in ageing dogs. J Reprod fertil 120:443–452

  • Saba CF, Rogers KS, Newman SJ, Mauldin GE, Vail DM (2007) Mammary gland tumors in male dogs. J Vet Intern Med 21:1056–1059. https://doi.org/10.1111/j.1939-1676.2007.tb03064.x

    Article  PubMed  Google Scholar 

  • Silva WM (2016) Neoplasia Mamária em Cadelas- Revisão de literatura. Dissertation, Equalis- Educação em Medicina Veterinária, Recife

  • Sorenmo KU, Deanna RW, Goldsmidt RH (2013) Tumors of the mammary gland. In: Withrow SJ, Vail DM. Withrow & MacEwen`s Small animal clinical oncology. 5° Ed. Philadelphia: W.B. Saunders Company

Download references

Author information

Authors and Affiliations

  1. Instituto Federal Catarinense- Campus Concórdia, Highway SC 283, km 17, Concórdia, Santa Catarina, 89703-720, Brazil

    Tainá Luana Vieira Lopes Zuchi, Júlia Balena Spricigo, Cláudia Luana Lopatini, Joice Lara Maia Faria, Eduardo Negri Mueller & Ricardo Evandro Mendes

  2. Laboratório de análises clínicas veterinária VETPAT, Street Coronel Manuel de Morais, 146, Jd. Brasil, Campinas, São Paulo, 13073-022, Brazil

    Felipe Augusto Ruiz Sueiro

Authors
  1. Tainá Luana Vieira Lopes Zuchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Júlia Balena Spricigo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Cláudia Luana Lopatini
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Joice Lara Maia Faria
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Eduardo Negri Mueller
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Felipe Augusto Ruiz Sueiro
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Ricardo Evandro Mendes
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Tainá Luana Vieira Lopes Zuchi.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zuchi, T.L.V.L., Spricigo, J.B., Lopatini, C.L. et al. Mammary gland carcinoma “in situ” in a male dog: case report. Comp Clin Pathol 27, 1097–1101 (2018). https://doi.org/10.1007/s00580-018-2733-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00580-018-2733-2

Keywords

Search

Navigation