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Sero-epidemiological study of peste des petits ruminants in small ruminants in Amahara region, Ethiopia

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Abstract

Peste des petits ruminants (PPR) is an acute, highly contagious, and economically important transboundary viral disease of sheep and goats. It is among the major infectious diseases that affect the production and productivity of small ruminants in Ethiopia. Cross-sectional and retrospective studies were undertaken to estimate the sero-prevalence, risk factors, and distribution of PPR in Amhara region. A total of 672 (329 sheep and 343 goats) sera were collected from 30 kebeles in 10 districts. Of the 672 sheep and goat sera samples tested using c-ELISA, 123 were positive for PPR antibodies, with the overall prevalence of 18.30% (95%CI 15.37, 21.24). The sero-prevalence of PPR was 21.57% (95%CI 17.15, 25.86) in goats and 14.89% (95%CI 10.96–18.65) in sheep. The variation of sero-prevalence among study zones was statistically significant (p < 0.05). The highest sero-prevalence was reported in Awi zone (55.34%) followed by South Gondar (15.89%), North Gondar (13.64%), East Gojjam (7.93%), and West Gojjam (6.62%) zones. Among host- and environment-related risk factors, species, sex, agro-ecology, and location of the study were significantly associated with PPR sero-positivity. The analysis of 5-year retrospective data (2010–2014) revealed high occurrence of PPR in the Amhara region with a total occurrence of 63 outbreaks (3978 cases and 919 deaths). In conclusion, the study revealed that PPR is an important and widely distributed disease of small ruminants in Amhara region. Appropriate control strategy including regular surveillance and vaccination is recommended to mitigate the challenge of PPR.

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Funding

This study was funded by the University of Gondar. The funding organization did not participate in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.

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Authors and Affiliations

  1. College of Veterinary Medicine and Animal Sciences, University of Gondar, P O Box 196, Gondar, Ethiopia

    Tsegaw Fentie, Birhanu Ayele, Wassie Molla, Seleshe Nigatu & Ashenafe Assefa

  2. Faculty of Agriculture, Debre Markos University, Debre Markos, Ethiopia

    Yechale Teshome

  3. College of Veterinary Medicine, Jigjiga University, Jigjiga, Ethiopia

    Nigusie Fenta

  4. College of Veterinary Medicine and Agriculture, Addis Ababa University, P. O. Box 34, Bishoftu, Ethiopia

    Samson Leta

Authors
  1. Tsegaw Fentie
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  2. Yechale Teshome
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  3. Birhanu Ayele
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  4. Wassie Molla
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  5. Nigusie Fenta
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  6. Seleshe Nigatu
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  7. Ashenafe Assefa
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  8. Samson Leta
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Correspondence to Samson Leta.

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Ethical approval

This research project was approved by the ethical review board of the University of Gondar. All efforts were made to minimize animal suffering during sample collection. Informed oral consents were obtained from all animal owners who participated in the study.

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The authors declare that they have no conflict of interest.

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Fentie, T., Teshome, Y., Ayele, B. et al. Sero-epidemiological study of peste des petits ruminants in small ruminants in Amahara region, Ethiopia. Comp Clin Pathol 27, 1029–1036 (2018). https://doi.org/10.1007/s00580-018-2697-2

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  • DOI: https://doi.org/10.1007/s00580-018-2697-2

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