Comparative Clinical Pathology

, Volume 26, Issue 2, pp 309–313 | Cite as

Proteomic impacts of electromagnetic fields on the male reproductive system

  • Masood SepehrimaneshEmail author
  • Devra Lee Davis
Review Article


The use of mobile phones and other wireless transmitting devices is increasing dramatically in developing and developed countries, as is the rate of infertility. A number of respected infertility clinics in Australia, India, USA, and Iran are reporting that those who regularly use mobile phones tend to have reduced sperm quantity and quality. Some experimental studies have found that human sperm exposed to electromagnetic fields (EMF), either simulated or from mobile phones, developed biomarkers of impaired structure and function, as well as reduced quantity. These encompass pathological, endocrine, and proteomic changes. Proteins perform a vast array of functions within living organisms, and the proteome is the entire array of proteins—the ultimate biomolecules in the pathways of DNA transcription to translation. Proteomics is the art and science of studying all proteins in cells, using different techniques. This paper reviews proteomic experimental and clinical evidence that EMF acts as a male-mediated teratogen and contributor to infertility.


Proteome Mobile phone Electromagnetic Male-mediated teratogen Blood-testis-barrier Heat-shock proteins 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Research involving human participants and/or animals

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

Due to the nature of review paper, no informed consent was available.


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Copyright information

© Springer-Verlag London 2016

Authors and Affiliations

  1. 1.Gastroenterohepatology Research CenterShiraz University of Medical SciencesShirazIran
  2. 2.Environmental Health TrustTeton VillageUSA

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