Abstract
A 3-month-old, 9.2 kg female Caucassian dog with primary complaint of growth at the lateral aspect of the right elbow was presented to the University of Nigeria, Nsukka Veterinary Teaching Hospital (UNVTH). Clinical examination revealed firm and roundish subcutaneous mass at the lateral aspect of the right elbow. Assessment of physiological parameters (temperature, respiratory, heart and pulse rates) revealed that they were normal. Haematology showed normal differential leukocytes count, but slightly decreased packed cell volume (PCV), red blood cell count (RBCs), haemoglobin concentration (HBC). Total leukocyte count (TLC) slightly increased. Serum biochemical assay revealed normal aspartate aminotransferase (AST) and alkaline phosphatase (ALP) activities, but slightly decrease alanine aminotransferase activity. Surgical excision was recommended based on the results of the clinical examination. Surgical excision of the mass was performed, and vincristine sulphate administered by intravenous injection at the dose of 0.75 mg/m2 once weekly for 3 weeks, post-surgically. No bacterial organism was isolated from cultured sample obtained from the excised mass. Histopathology revealed non-encapsulated, dense interlacing and interconnecting bundles of immature fibroblastic cells with some neovascularization, and mitotic figures were rarely seen averaging two mitoses per high power field. The nuclei uniformly appeared to be slightly larger than those of normal fibroblasts. The cytoplasms were continuous with the dense collagenous stroma basically arranged in interwoven bundles. Diagnosis of cutaneous myxoma was based on the results of clinical and histopathological examinations. Surgical excision and post-surgical administration of vincristine sulphate were very effective with no recurrence during 6 months follow-up period. This report has shown that cutaneous myxoma could occur in Cuacassian dogs.
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Udegbunam, S.O., Udegbunam, R.I., Nnaji, T.O. et al. Unusual occurrence of cutaneous myxoma in a Caucassian dog: a short communication. Comp Clin Pathol 24, 945–950 (2015). https://doi.org/10.1007/s00580-014-2047-y
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DOI: https://doi.org/10.1007/s00580-014-2047-y