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Comparative Clinical Pathology

, Volume 24, Issue 3, pp 555–560 | Cite as

Comparative study of therapeutic protocols used in the treatment of infections caused by rickettsiales in dogs

  • Adriana Jardim de AlmeidaEmail author
  • Hayla Felix Rodrigues
  • Ana Bárbara Freitas Rodrigues
  • Paula Alessandra Di Filippo
  • Anderson Barros Teixeira Pinto
Original Article
  • 129 Downloads

Abstract

Tick-borne diseases are caused by rickettsiales microorganisms of the genera Anaplasma and Ehrlichia, and often are diagnosed in dogs (Canis familiaris). Therapeutic protocols include antibiotics of different classes, mainly tetracyclines and derivatives. This comparative study contrasts two treatment protocols routinely used in veterinary medicine to treat Rickettsiosis and assesses the respective hematological changes. Dogs used for this research were divided in two groups: group 1, treated with long-acting oxytetracycline 15 mg kg−1 and group 2, treated with doxycycline 10 mg kg−1. The results showed that blood smears of both groups were negative for rickettsiales after therapy, with no morulae in peripheral blood samples. Hematology findings differed between animals before and after treatments. The most relevant data showed that the most common hematological changes before treatments were thrombocytopenia, anemia, and leukocytosis with eosinophilia. Both treatments were effective to treat dogs infected with Rickettsiales, and platelet counts increased in thrombocytopenic dogs after treatment, in both therapy protocols.

Keywords

Hemoparasite Canine Treatment Rickettsia 

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Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  • Adriana Jardim de Almeida
    • 1
    Email author
  • Hayla Felix Rodrigues
    • 2
  • Ana Bárbara Freitas Rodrigues
    • 3
  • Paula Alessandra Di Filippo
    • 1
  • Anderson Barros Teixeira Pinto
    • 1
  1. 1.Laboratory of Animal Clinic and SurgeryUENFCampos dos GoytacazesBrazil
  2. 2.Veterinary Hospital Vet D’orCabo FrioBrazil
  3. 3.Laboratory of Animal Morphology and PathologyUENFCampos dos GoytacazesBrazil

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