Abstract
Measurement of anti-Müllerian hormone (AMH) is applied to diagnose polycystic ovary syndrome in human. A 7-year-old female Persian cat was presented for persistent expression of behavioural oestrus. In response to examination of spines, the queen exhibited treading movements of hind legs. Trans-abdominal ultrasonography revealed a multicystic appearance of both ovaries. Oestradiol in the queen with prolonged oestrus (145 pg/ml) was higher than that in normal oestrous cats (50.8 ± 7.41 pg/ml). However, AMH concentration in the cat with prolonged oestrus (1.8 ng/ml) was within the range of AMH concentration in normal oestrous queens (3.5 ± 0.81 ng/ml; range, 1.2–5.8 ng/ml). The queen was diagnosed with cystic ovarian disease and was subjected to ovariohysterectomy. Excision and histopathology confirmed cystic ovarian disease as well as uterine hyperplasia. In conclusion, it seems that AMH could not serve as a diagnostic indicator of cystic ovarian disease in cat.
References
Boomsma RA, Verhage HG (1982) The uterine progestational response in cats: ultrastructural changes during chronic administration of progesterone to estradiol-primed and nonprime animals. Am J Anat 164:243–254
Boomsma RA, Jaffe RC, Verhage HG (1982) The uterine progestational response in cats: changes in morphology and progesterone receptors during chronic administration of progesterone to estradiol-primed and nonprimed animals. Biol Reprod 26:511–521
Bristol-Gould S, Woodruff TK (2006) Folliculogenesis in the domestic cat (Felis catus). Theriogenology 66:5–13
Chatdarong K, Rungsipipat A, Axnér E et al (2005) Hysterographic appearance and uterine histology at different stages of the reproductive cycle and after progestagen treatment in the domestic cat. Theriogenology 64:12–29
Fallat ME, Siow Y, Marra M et al (1997) Müllerian-inhibiting substance in follicular fluid and serum: a comparison of patients with tubal factor infertility, polycystic ovary syndrome, and endometriosis. Fertil Steril 67:962–965
Franks S, Mason H, Willis D (2000) Follicular dynamics in the polycystic ovary syndrome. Mol Cell Endocrinol 163:49–52
Gelberg HB, McEntee K, Heath EH (1984) Feline cystic rete ovarii. Vet Pathol 21:304–307
Gharagozlou F, Youssefi R, Akbarinejad V et al (2013) Evaluation of serum anti-Müllerian hormone (AMH) in two mares with hemorrhagic anovulatory follicle. Comp Clin Pathol. doi:10.1007/s00580-013-1785-6
Johnston SD, Root Kustritz MV, Olson PS (2001) Disorders of the feline ovaries. In: Johnston SD, Root Kustritz MV, Olson PS (eds) Canine and feline theriogenology. Saunders, Philadelphia, pp 453–462
La Marca A, Volpe A (2006) Anti-Müllerian hormone (AMH) in female reproduction: is measurement of circulating AMH a useful tool? Clin Endocrinol 64:603–610
Monniaux D, di Clemente N, Touze JL et al (2008) Intrafollicular steroids and anti-Müllerian hormone during normal and cystic ovarian follicular development in the cow. Biol Reprod 79:387–396
Munsterberg A, Lovell-Badge R (1991) Expression of the mouse anti-Müllerian hormone gene suggests a role in both male and female sexual differentiation. Development 113:613–624
Perez JF, Conley AJ, Dieter JA et al (1999) Studies on the origin of ovarian interstitial tissue and the incidence of endometrial hyperplasia in domestic and feral cats. Gen Comp Endocrinol 116:10–20
Place NJ, Hansen BS, Cheraskin J-L et al (2011) Measurement of serum anti-Müllerian hormone concentration in female dogs and cats before and after ovariohysterectomy. J Vet Diagn Investig 23:524–527
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Gharagozlou, F., Youssefi, R., Akbarinejad, V. et al. Evaluation of serum anti-Müllerian hormone (AMH) in a Persian queen cat with bilateral cystic ovarian disease. Comp Clin Pathol 23, 237–239 (2014). https://doi.org/10.1007/s00580-013-1822-5
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DOI: https://doi.org/10.1007/s00580-013-1822-5