Skip to main content
SpringerLink
Log in

Dietary Berberis vulgaris extract enhances intestinal mucosa morphology in the broiler chicken (Gallus gallus)

Comparative Clinical Pathology Aims and scope Submit manuscript

Cite this article

Abstract

To determine the effect of Berberis vulgaris extract on the intestinal morphology, 1-day-old broiler chickens had their diet supplemented with 2 and 4 % barberry water extract for 3 days. On day 45, all chicks in each group were killed and morphometric analysis of the intestine was performed. The duodenal villous length and surface area were significantly (P < 0.05) increased in the 4 % barberry water extract-supplemented group. The jejunal villous length was significantly (P < 0.05) increased in all treatment groups when compared with the control group. No significant differences were observed between the two treatment groups. The ileal villous surface area in all the treatment groups was greater than the control group, but this increase was not significantly different (P > 0.05). In conclusion, barberry water extract supplementation, particularly at a value of 4 %, can increase the majority of the intestinal architecture in broiler chickens.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  • Asfar S, Abdeen S, Dashti H, Khoursheed M, Al-Sayer H, Mathew T, Al-Bader A (2003) Effect of green tea in the prevention and reversal of fasting-induced intestinal mucosal damage. Nutrition 19:536–540

    Article  PubMed  CAS  Google Scholar 

  • Assis RCL, Luns FD, Beletti ME, Assis RL, Nasser NM, Faria ESM, Cury MC (2010) Histomorphometry and macroscopic intestinal lesions in broilers infected with Eimeria acervulina. Vet Parasitol 168:185–189

    Article  PubMed  CAS  Google Scholar 

  • Awad WA, Ghareeb K, Abdel-Raheem S, Bohm J (2009) Effects of dietary inclusion of probiotic and synbiotic on growth performance, organ weights, and intestinal histomorphology of broiler chickens. Poult Sci 88:49–55

    Article  PubMed  CAS  Google Scholar 

  • Garcia V, Catala-Gregori P, Hernandez F, Megias MD, Madrid J (2007) Effect of formic acid and plant extracts on growth, nutrient digestibility, intestine mucosa morphology, and meat yield of broilers. J Appl Poult Res 16:555–562

    Article  CAS  Google Scholar 

  • Geyra A, Uni Z, Sklan D (2001) Enterocyte dynamics and mucosal development in the posthatch chick. Poult Sci 80:776–782

    PubMed  CAS  Google Scholar 

  • Giannenas I, Tontis D, Tsalie E, Chronis EF, Doukas D, Kyriazakis I (2010) Influence of dietary mushroom Agaricus bisporus on intestinal morphology and microflora composition in broiler chickens. Res Vet Sci 89:78–84

    Article  PubMed  CAS  Google Scholar 

  • Hassanpour H, Bahadoran S, Koosha S, Askari E, Homai S (2010a) Effect of diclazuril, semduramicin, salinomycin and maduramycin as preventive anticoccidial drugs on chicken intestinal morphology. Global Vet 5:1–5

    CAS  Google Scholar 

  • Hassanpour H, Zamani Moghaddam AK, Yazdani A, Cheraghchi Bashi M (2010b) Evaluation of intestinal morphology and nitric oxide metabolites in broiler chickens supplemented by green tea. Comp Clin Pathol 19:43–47

    Article  CAS  Google Scholar 

  • Imanshahidi M, Hosseinzadeh H (2008) Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phyto Res 22:999–1012

    Article  CAS  Google Scholar 

  • Kupeli E, Kosar M, Yesilada E, Husnu K, Baser C (2002) A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. Life Sci 72:645–657

    Article  PubMed  CAS  Google Scholar 

  • Miller MJS, Angeles FM, Reuter BK, Bobrowski P, Sandoval M, Neuhausen SL, Feolo M, Farnham J, Book L, Zone JJ (2001) Dietary antioxidants protect gut epithelial cells from oxidant induced apoptosis. BMC Comp Alter Med 1:11

    Article  CAS  Google Scholar 

  • Rajaian H, Jalaee J, Aghajani A (2006) Berberis vulgaris as growth promotor in broiler chickens. Inter J Poult Sci 5:395–397

    Article  Google Scholar 

  • Sakamoto K, Hirose H, Onizuka A, Hayashi M, Futamura N, Kawamura Y, Ezaki T (2000) Quantitative study of changes in intestinal morphology and mucus gel on total parenteral nutrition in rats. J Surg Res 94:99–106

    Article  PubMed  CAS  Google Scholar 

  • Silva MA, Pessotti BMS, Zanini SF, Colnago GL, Rodrigues MRA, Nunes LC, Zanini MS, Martins IVF (2009) Intestinal mucosa structure of broiler chickens infected experimentally with Eimeria tenella and treated with essential oil of oregano. Ciencia Rural 39:1471–1477

    Article  Google Scholar 

  • Teirlynck E, Bjerrum L, Eeckhaut V, Huygebaert G, Pasmans F, Haesebrouck F, Dewulf J, Ducatelle R, Van Immersee F (2009) The cereal type in feed influences gut wall morphology and intestinal immune cell infiltration in broiler chickens. Bri J Nut 102:1453–1461

    Article  CAS  Google Scholar 

  • Windisch W, Schedle K, Plitzner C, Kroismayr A (2008) Use of phytogenic products as feed additives for swine and poultry. J Anim Sci 86:140–148

    Article  Google Scholar 

  • Yesilada E, Kupeli E (2002) Berberis crataegina DC. root exhibits potent anti-inflammatory, analgesic and febri-fuge effects in mice and rats. J Ethnopharmacol 79:237–248

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

These studies were conducted as part of Broiler Production Programme, administered by School of Veterinary Medicine, Shiraz University. The authors wish to thank everybody who assisted in sampling and determination of all the parameters and Professor H. Dadras for his valuable discussions.

Author information

Authors and Affiliations

  1. Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, Iran

    A. Yazdani, S. L. Poorbaghi, H. Habibi & S. Nazifi

  2. Department of Basic Sciences, School of Veterinary Medicine, Shiraz University, P.O. Box: 71345-1731, Shiraz, Iran

    F. Rahmani Far & M. Sepehrimanesh

Authors
  1. A. Yazdani
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. L. Poorbaghi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Habibi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. S. Nazifi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. F. Rahmani Far
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. M. Sepehrimanesh
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. Sepehrimanesh.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Yazdani, A., Poorbaghi, S.L., Habibi, H. et al. Dietary Berberis vulgaris extract enhances intestinal mucosa morphology in the broiler chicken (Gallus gallus). Comp Clin Pathol 22, 611–615 (2013). https://doi.org/10.1007/s00580-012-1454-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00580-012-1454-1

Keywords

search

Navigation