Abstract
A male 2.5-year-old American short hair cat was admitted to the animal hospital with the primary complaints of abdominal distension and depression for several days. Ultrasound revealed a large hypoechoic cavity with a well demarcated thin wall on a liver lobe. On exploratory laparotomy, a hepatic haematoma was observed. Subsequently, hepatic lobectomy was performed. Histologically, an eosinophilic substance stained with Congo red was deposited in the cyst wall which showed an optical property of apple green birefringence under polarized light. Based on immunohistochemical staining, amyloid A was diagnosed. To our knowledge, this is the first report of a spontaneous hepatic haematoma with an amyloid A deposition in a cat.
References
Beatty JA, Barrs VR, Martin PA, Nicoll RG, France MP, Foster SF, Lamb WA, Malik R (2002) Spontaneous hepatic rupture in six cats with systemic amyloidosis. J Small Anim Pract 43:355–363
Boyce JT, DiBartola SP, Chew DJ, Gasper PW (1984) Familial renal amyloidosis in Abyssinian cats. Vet Pathol 21:33–38
Buxbaum J (2006) The genetics of amyloidoses: interactions with immunity and inflammation. Genes Immun 7:439–449
Culp WTN, Weisse C, Kellog ME, Gordon IK, Clarke DL, May LR, Drobatz KJ (2010) Spontaneous hemoperitoneum in cats: 65 cases (1994–2006). JAVMA 236:978–982
Ensari C, Ensari A, Tümer N, Ertug E (2005) Clinicopathological and epidemiological analysis of amyloidosis in Turkish patients. Nephrol Dial Transplant 20:1721–1725
Gillmore JD, Hawkins PN, Pepys MB (1997) Amyloidosis: a review of recent diagnostic and therapeutic developments. Br J Haematol 99:245–256
Simons FA, Vennema H, Rofina JE, Pol JM, Horzinek MC, Rottier PJM, Egberink HF (2005) A mRNA PCR for the diagnosis of feline peritonitis. J Virol Methods 124:111–116
Van Der Linde-Sipman JS, Niewold TA, Tooten PC, De Neijs-Backer M, Gruys E (1997) Generalized AA—amyloidosis in Siamese and Oriental cats. Vet Immunol Immunopathol 56:1–10
WHO–IUIS Nomenclature Sub-Committee (1993) Nomenclature of amyloid and amyloidosis. Bull World Health Org 71:105–112
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Prihirunkit, K., Sutthiprapa, W. Spontaneous hepatic haematoma in a cat. Comp Clin Pathol 21, 353–355 (2012). https://doi.org/10.1007/s00580-012-1409-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00580-012-1409-6