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The possible role of zinc in excessive shedding of hair in two Persian cats

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This study was conducted to identify the possible correlation between zinc deficiency and excessive shedding of hair in cats. Two male cats aged 2 and 3 years old, Persian breeds, and weighing 2.9 and 3.2 kg were presented to the Veterinary Hospital of Shahid Chamran University with chief complaints of excessive shedding of hair, depressed appetite, and weight loss in the past month. Physical examination revealed a relatively weak body condition. Serum zinc, copper, calcium, and iodine concentrations were measured using commercially available kits (Randox Laboratories, UK) with a spectrophotometer (Shimadzu, UV-1601). Total protein concentrations were assessed with a refractometer also. A decrease in zinc concentrations (35 and 41 μg/dl) was observed in the studied cats, respectively. Based on the clinical history, physical examination, biochemical analysis, and response to treatment, zinc absolute deficiency was diagnosed. In this survey, the status of copper, calcium, iodine concentrations, and total proteins was normal. To the best of the authors' knowledge, there was no report of zinc deficiency in pet animals in Iran. A possible relationship between zinc deficiency and excessive shedding of hair has been reported in the present survey.

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  • Colombini S (1999) Canine zinc-responsive dermatosis. Vet Clin North Am Small Anim Pract 29:1373–1383

    PubMed  CAS  Google Scholar 

  • Evans P, Halliwell B (2001) Micronutrients: oxidant/antioxidant status. Br J Nutr 85:67–74

    Article  Google Scholar 

  • Forlano M, Scofield A, Elisei C, Fernandes KR, Ewing SA, Massard CL (2005) Diagnosis of Hepatozoon spp. in Amblyomma ovale and its experimental transmission to domestic dogs in Brazil. Vet Parasitol 134:1–7

    Article  PubMed  CAS  Google Scholar 

  • Gabor S (1989) Trace elements and lipid peroxidation. In: Yuregir GT, Donma O, Kayrin L (eds) Trace elements in health and disease, vol 89. Adana, Turkey, pp 273–277

    Google Scholar 

  • Kane E, Morris JG, Rogers OR (1981) Zinc deficiency in the cat. J Nutr 111:488–495

    PubMed  CAS  Google Scholar 

  • Rand ML, Murray RK (2000) Plasma proteins, immunoglobulins and blood coagulation. In: Harpers biochemistry, des. Murray RK, Granner DK, Mayes PA, Rodwell VW, 25th ed. Appleton and Lange, Stamford, pp 741–744

  • Scott DW, William HM, Griffin CE (2001) Nutritional skin diseases. In: Muller and Kirk's small animal dermatology, 6th edn. W. B. Saunders Co, Philadelphia, pp 891–901

    Google Scholar 

  • Tasci S, Sengil AZ, Altindis M, Arisoy K (1995) The effect of zinc supplementation in experimentally induced Toxoplasma gondii infection. J Egypt Soc Parasitol 25:745–751

    PubMed  CAS  Google Scholar 

  • Tilley LP, Smith FWK (2007) The 5-minute veterinary consult, 3rd edn. Lippincott Williams and Wilkins, Maryland, p 1322

    Google Scholar 

  • Watson TDG (1998) Diet and skin disease in dogs and cats. J Nutr 128:2783–2789

    Google Scholar 

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Correspondence to Bahman Mosallanejad.

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Mosallanejad, B., Avizeh, R. The possible role of zinc in excessive shedding of hair in two Persian cats. Comp Clin Pathol 21, 213–215 (2012).

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