Abstract
Two groups of high- and average-producing dairy cows (HPDCs and APDCs, respectively), 50 in each group, were randomly selected from two farms near Shiraz, Fars province, Iran. From each cow in both herds, jugular vein blood samples were collected, 1 month before estimated calving, at calving, and also at 1, 2, and 3 months after calving. Sera were analyzed for zinc, copper, molybdenum, cobalt, manganese, and iron by atomic absorption spectrophotometry. All cows in this study, either during the dry period, following parturition or during the postpartum period were examined for body condition scores and record of reproductive indices. Results showed a significant decline in zinc serum concentrations in high and average producing dairy cows at calving, when compared to corresponding levels of zinc, 1 month before estimated calving (p < 0.05). No significant changes were found in serum zinc concentrations between the HPDCs and APDCs in all states. There was a nonsignificant increase in serum levels of copper at calving in HPDCs and APDCs when compared to the corresponding levels of copper 1 month before estimated calving. The serum concentrations of copper showed no significant variations between HPDCs and APDCs in different states. No significant changes were seen in concentrations of cobalt, manganese, molybdenum, or iron in different states of production. A significant negative correlation between the zinc and copper concentrations (r = −0.32, p < 0.05) was found 3 months after calving in APDCs.
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Aihara K, Nishi Y, Hatano S, Kihara M, Yoshimitsu K, Takeichi NHI, Ezaki H, Usui T (1984) Zinc, copper, manganese, and selenium metabolism in thyroid disease. Am J Clin Nutr 40:26–35
Andrieu S (2008) Is there a role for organic trace element supplements in transition cow health? Vet J 176:77–83
Ansotegui RP, Bailey JD, Paterson JA, Hatfield PG, Swenson CK (1999) Effects of supplemental trace mineral form on copper status, estrus, ovulation rate, and fertility in beef heifers. Am Soc Anim Sci 50:189–192
Boland MP, Lonergan P (2003) Trace minerals in production and reproduction in dairy cows. AdvDairy Technol 15:19–33
Bouman AA, Platenkamp AJ, Posma FD (1986) Determination of cobalt in urine by flameless atomic absorption spectroscopy. Comparison of direct analysis using Zeeman background correction and indirect analysis using extraction in organic solution. Ann Clin Biochem 23:346–350
Ceylan A, Serin I, Aksit H, Seyrek K (2008) Concentrations of some elements in dairy cows with reproductive disorders. Bull Vet Inst Pulawy 52:109–112
Conner JG, Eckersall PD, Doherty M, Douglas TA (1986) Acute phase response and mastitis in the cow. Res Vet Sci 41:126–128
Corah LR, Ives S (1991) The effects of essential trace minerals on reproduction in beef cows. Vet Clin North Am Food Anim Pract 7:41–57
Cunnane SC, Harbige LS, Crawford MA (1993) The importance of energy and nutrient supply in human brain evolution. Nutr Health 9:219–235
Dehaan JB, Tymms MJ, Cristiano F, Kola I (1994) Expression of copper/zinc superoxide dismutase and glutathione peroxidase in organs of developing mouse embryos, fetuses and neonates. Ped Res 35:188–196
Ferguson JD, Galligan DT, Thomsen N (1994) Principal descriptors of body condition score in Holstein cows. J Dairy Sci 77:2695–2703
Goff JP, Stabel JR (1990) Decreased plasma retinol, α-tocopherol and zinc concentration during the peripartum period: effect of milk fever. J Dairy Sci 73:3195–3199
Graham TW, Thurmond MC, Mohr FC, Holmberg CA, Anderson L, Keen CL (1994) Relationsheep between maternal and fetal liver copper, iron, manganese and zinc concentrations and fetal development in California Holstein dairy cows. J Vet Diagn Invest 6:77–87
Harmon RJ, Torre PM (1997) Economic implications of copper and zinc proteinates: role in mastitis control. In: Lyons TP, Jacques KA (eds) Biotechnology in the feed industry. Nottingham University Press, Nottingham, pp 419–430
Hidiroglou M (1979) Element deficiencies and fertility in ruminants: a review. J Dairy Sci 62:1995–2206
Hostetler CE, Kincaid RL, Mirando MA (2003) Role of essential trace elements in embryonic and fetal development in livestock. Vet J 166:125–139
Johnston LA, Chew BP (1984) Peripartum changes of plasma and milk vitamin A and β-carotene among dairy cows with or without mastitis. J Dairy Sci 67:1832–1840
Jovanovic-Peterson L, Peterson CM (1996) Vitamin and mineral deficiencies, which may predispose to glucose intolerance of pregnancy. J Am Coll Nutr 15:14–20
Judson GJ, McFarlane JD, Mitsioulis A, Zviedrans P (1997) Vitamin B12 responses to cobalt pellets in beef cows. Aust Vet J 75:660–662
Lauber K (1978) determination of serum iron; a comparison of two methods: atomic absorption and bathophenanthroline without deproteinisation. J Clin Chem Clin Biochem 16:315–316
Leach RM (1967) Role of manganese in the synthesis of mucopolysaccharides. Federation Proc 26:118–120
MacPherson A, Moon FE, Voss RC (1973) Some effects of feedin young steers on a diet deficient inboth cobalt and copper. Br Vet J 129:414–425
Madhavan E, Iyer CPN (1993) Treatment of anoestrus in crossbred cows with CoCu-H. Indian J Anim Reprod 14:125–132
McClure TJ (1994) Nutritional and metabolic infertility in the cow. CAB International, Singapore, pp 39–61
Meglia GE, Johannisson A, Petersson L, Persson Waller K (2001) Changes in some blood micronutrients, leukocytes and neutrophil expression of adhesion molecules in periparturient dairy cows. Acta Vet Scand 42:139–150
Michal JJ, Heirman LR, Wong TS, Chew BP, Frigg M, Volker L (1994) Modulatory effects of dietary β-carotene on blood and mammary leukocyte function in periparturient dairy cows. J Dairy Sci 77:1408–1421
NRC (2001) Nutrient requirements of dairy cows. 7th rev. ed. Natl. Acad. Sci., Washington, DC
Prohaska JR, Lukasewycz OA (1990) Effect of copper deficiency on the immune system. Adv Exper Med Biol 262:123–143
Raub TJ, Bazer FW, Roberts RM (1985) Localization of the iron transport glycoprotein, uteroferrin, in the porcine endometrium and placenta by using immunocolloidal gold. Anat Embryol 171:253–258
Reddy PG, Frey RA (1990) Nutritional modulation of immunity in domestic food animals. Adv Vet Sci Comp Med 35:255–281
Smith KL, Hogan JS, Weiss WP (1997) Dietary vitamin E and selenium affect mastitis and milk quality. J Anim Sci 75:1659–1665
Spears JW, Harvey RW, Brown TT (1991) Effects of zinc methionine and zinc oxide on performance, blood characteristics, and antibody titer response to viral vaccination in stressed feeder calves. JAVMA 199:1731–1733
Townsend SF, Briggs KK, Krebs NF, Hambridge KF (1994) Zinc supplementation selectively decreases fetal hepatocyte DNA synthesis and insulin-like growth factor II gene expression in primary culture. Ped Res 35:404–408
Underwood EJ (1981) The mineral nutrition of livestock, 2nd edn. Commonwealth Agricultural Bureaux, Farnham Royal, pp 135–142
Uriu-Adams JY, Keen CL (2005) Copper, oxidative stress, and human health. Mol Aspects Med 26:268–298
Weiss WP, Hogan JS, Smith KL, Hoblet KH (1990) Relationships among selenium, vitamin E, and mammary gland health in commercial dairy herds. J Dairy Sci 73:381–390
Xin Z, Waterman DF, Hemken RW, Harmon RJ (1993) Copper status and requirement during the dry period and early lactation in multiparous Holstein cows. J Dairy Sci 76:2711–2716
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The authors wish to thank the financial support of the Center of Excellence for Studying on High Producing Dairy Cows of Shiraz University and high collaboration of Central Laboratory of the School of Veterinary Medicine.
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Badiei, K., Orangi, H., Mostaghni, K. et al. Serum trace minerals in different physiological states of high- and average-producing dairy cows. Comp Clin Pathol 20, 427–431 (2011). https://doi.org/10.1007/s00580-010-1012-7
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DOI: https://doi.org/10.1007/s00580-010-1012-7