Evaluation of the Sysmex XT-2000iV haematology analyser for rat, dog and mouse whole blood samples

  • R. A. MathersEmail author
  • G. O. Evans
  • J. Bleby
  • T. Tornow
Original Article


The Sysmex XT-2000iV is a dedicated haematology analyser with full blood count, reticulocyte and five-population differential leucocyte capabilities for several laboratory animal species. The laboratory animal species chosen for this study were rat, dog and mouse. Results from dipotassium ethylenediamine tetraacetic acid (K2EDTA) samples from these species were compared with the laboratory’s established haematology analyser, the Bayer (now Siemens) Advia 120™ with multispecies software (Siemens Medical Solutions Diagnostics Europe Limited, Frimley, UK). Imprecision, carry-over between samples, linearity and stability data were also studied. In addition, results obtained for leucocyte differential counts were compared with standard manual 100-cell counts. Throughout this study, the Sysmex XT-2000iV proved to be robust, reliable and dependable. In summary, the Sysmex XT-2000iV has proved capable of accurately and precisely producing haematology results for animal species used within the pharmaceutical industry.


Haematology analyser Sysmex XT-2000iV Rat blood Mouse blood Dog blood 


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Copyright information

© Springer-Verlag London Ltd 2008

Authors and Affiliations

  • R. A. Mathers
    • 1
    Email author
  • G. O. Evans
    • 1
  • J. Bleby
    • 2
  • T. Tornow
    • 3
  1. 1.Clinical Pathology, Safety AssessmentLoughborough,UK
  2. 2.Sysmex UK LtdWymbush,UK
  3. 3.Sysmex Europe GmbHNorderstedtGermany

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