Skip to main content
Log in

Transcatheter Closure of Secundum Atrial Septal Defects Using the Amplatzer Septal Occluder: Initial Experience in Taiwan

  • Surgical
  • Published:
International Journal of Angiology

Abstract

We assessed the safety and efficacy of closure of secundum-type atrial septal defects (ASDs) using the Amplatzer septal occluder (ASO) in a sample of Taiwanese patients. Between June 2000 and April 2002, 25 patients underwent transcatheter closure of their secundum-type atrial septal defect/s using the ASO device. The procedures were performed under general anesthesia with access through the femoral vein using guidance provided by transoesophageal echocardiography (TEE) and fluoroscopy. Twenty-two patients had larger defects with right cardiac dilatation and paradoxical interventricular septal motion, while family concerns were the primary indications for closure for the other three. Twenty-five ASO devices were successfully implanted in 24 patients, with a lone individual referred for surgery due to implantation failure. The mean age of the patients was 12.5 years. The male-female ratio was 12:13. The mean pulmonary-systemic blood flow ratio (Qp:Qs) was 2.5:1. The ASD size (mean 20.2 mm; range 8–28.5) was measured using transoesophageal echocardiography, with a balloon-stretched diameter of 8–29.5 mm (mean 20.5). The size of the implanted devices ranged from 9–36 mm (mean 23.1). Fluoroscopy duration ranged from 9.7–41.2 minutes (mean 23.5). A residual shunt, assessed not significant from transoesophageal echocardiography, was detected in one patient who had received two ASO devices for multiple ASDs. Follow-up intervals ranged from 0.1–2 years (median 1.0), with no late complications determined for any patient. Transcatheter closure of secundum ASDs using the Amplatzer septal occluder is a safe and effective alternative to the surgical analog. With careful selection of patients, secundum ASDs can be successfully closed, with minimal procedural morbidity and excellent early results. Long-term follow up is necessary for evaluation, however, if this procedure is to be as effective as surgery.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. GW Vick III (1998) Defects of the atrial septum including atrioventricular septal defects. A Garson Jr JT Bricker DJ Fisher SR Neish (Eds) The science and practice of pediatric cardiology, Vol. I. Williams & Wilkins Baltimore 1141–1179

    Google Scholar 

  2. RH Feldt P Avasthey F Yoshimasu (1971) ArticleTitleIncidence of congenital heart disease in children born to residents of Olmsted County, Minnesota, 1950–1969. Mayo Clin Proc 46 794–799 Occurrence Handle1:STN:280:CS2D28vpsF0%3D Occurrence Handle5128021

    CAS  PubMed  Google Scholar 

  3. RJ Craig A Selzer (1968) ArticleTitleNatural history and prognosis of atrial septal defect. Circulation 37 805–815 Occurrence Handle1:STN:280:CCeB3c7jsVM%3D Occurrence Handle5646864

    CAS  PubMed  Google Scholar 

  4. DG Ruschhaupt L Khoury OG Thilenius (1984) ArticleTitleElectrophysiologic abnormalities of children with ostium secundum atrial septal defect. Am J Cardiol 53 IssueID11 1643–1647 Occurrence Handle1:STN:280:BiuB38fisVc%3D Occurrence Handle6731310

    CAS  PubMed  Google Scholar 

  5. BD Thanopoulos CV Laskari GS Tsaousis (1998) ArticleTitleClosure of atrial septal defects with the Amplatzer occlusion device: preliminary results. J Am Coll Cardiol 31 1110–1116 Occurrence Handle10.1016/S0735-1097(98)00039-4 Occurrence Handle1:STN:280:DyaK1c3itVCrsA%3D%3D Occurrence Handle9562015

    Article  CAS  PubMed  Google Scholar 

  6. KC Chang MJ Godman K Walsh (1999) ArticleTitleTranscatheter closure of atrial septal defect and interatrial communications with new self-expanding nitinol double disc device (Amplatzer septal occluder): multicentre UK experience. Heart 82 300–306 Occurrence Handle10455079

    PubMed  Google Scholar 

  7. J Losay J Petit V Lambert (2001) ArticleTitlePercutaneous closure with Amplatzer device is a safe and efficient alternative to surgery in adults with large atrial septal defects. Am Heart J 142 IssueID3 544–548 Occurrence Handle10.1067/mhj.2001.116757 Occurrence Handle1:STN:280:DC%2BD3Mvot1KhtQ%3D%3D Occurrence Handle11526371

    Article  CAS  PubMed  Google Scholar 

  8. QL Cao ZD Du A Joseph (2001) ArticleTitleImmediate and six-month results of the profile of the Amplatzer septal occluder as assessed by transesophageal echocardiography. Am J Cardiol 88 IssueID7 754–759 Occurrence Handle10.1016/S0002-9149(01)01846-X Occurrence Handle1:STN:280:DC%2BD3MrktlCgsQ%3D%3D Occurrence Handle11589842

    Article  CAS  PubMed  Google Scholar 

  9. DA Jones DJ Radford PG Pohlner (2001) ArticleTitleOutcome following surgical closure of secundum atrial septal defect. J Paediatr Child Health 37 IssueID3 274–277 Occurrence Handle10.1046/j.1440-1754.2001.00659.x Occurrence Handle1:STN:280:DC%2BD3Mvhsl2hsg%3D%3D Occurrence Handle11468044

    Article  CAS  PubMed  Google Scholar 

  10. R Formigari RM Di Donato E Mazzera (2001) ArticleTitleMinimally invasive or interventional repair of atrial septal defects in children: experience in 171 cases and comparison with conventional strategies. J Am Coll Cardiol 37 IssueID6 1707–1712 Occurrence Handle10.1016/S0735-1097(01)01213-X Occurrence Handle1:STN:280:DC%2BD3M3ktFSlug%3D%3D Occurrence Handle11345388

    Article  CAS  PubMed  Google Scholar 

  11. AS Dajani KA Taubert W Wilson (1997) ArticleTitlePrevention of bacterial endocarditis. Recommendations by The American Heart Association. JAMA 277 1794–1801 Occurrence Handle10.1001/jama.277.22.1794 Occurrence Handle1:STN:280:ByiA383htl0%3D Occurrence Handle9178793

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ta-Cheng Huang M.D..

About this article

Cite this article

Hsieh, KS., Lee, CL., Lin, CC. et al. Transcatheter Closure of Secundum Atrial Septal Defects Using the Amplatzer Septal Occluder: Initial Experience in Taiwan . International Journal of Angiology 12, 122–124 (2003). https://doi.org/10.1007/s00547-003-0943-0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00547-003-0943-0

Keywords

Navigation