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Processability and biodegradability of polylactic acid nasal implants

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Abstract

In the current study, we produce a biodegradable scaffold used as an absorbable nasal implant by using polylactic acid (PLA). A new design for the biodegradable implant was introduced, and produced via insert injection molding. A metal part was inserted into a mold for the processing. A three-dimensional numerical analysis based on the finite element methods was employed to predict melt front advancement and optimize process condition. Two kinds of samples with different lengths were manufactured and compared in terms of the rheological behavior and warpage deformation. The change of density in the injection molded part was simulated, and the degree of biodegradation was evaluated with respect to time.

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Data availability

The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

This work was supported by GRRC program of Gyeonggi Province (GRRC Dankook2016-B03). In addition, this research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education (Nos. NRF-2021R1F1A1051256 and 2018R1A5A1024127). The authors are grateful for the supports.

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Authors and Affiliations

  1. Department of Convergence Systems Engineering, Dankook University, Yongin-si, 16890, Gyeonggi-do, Korea

    Zheng Min Huang

  2. JINOH Mechadical Inc, Gunpo-si, 15845, Gyeonggi-do, Korea

    Hwa Jin Oh

  3. Department of Fiber Convergence Materials Engineering, Dankook University, Yongin-si, 16890, Gyeonggi-do, Korea

    Young Seok Song

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  1. Zheng Min Huang
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  2. Hwa Jin Oh
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  3. Young Seok Song
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Correspondence to Young Seok Song.

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Huang, Z.M., Oh, H.J. & Song, Y.S. Processability and biodegradability of polylactic acid nasal implants. Microsyst Technol 29, 265–270 (2023). https://doi.org/10.1007/s00542-023-05418-9

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  • DOI: https://doi.org/10.1007/s00542-023-05418-9

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