Abstract
Magnetometer is one of the indispensable instruments utilized for the magnetic property characterization of materials, where it evaluates the magnetic response originated from the materials. The non-invasive magnetic technique has promoted magnetometer to be utilized in new applications such as in biomedical applications. In this work, we report the development of a magnetometer utilizing a high critical temperature superconducting quantum interference device (high-Tc SQUID) and a flux transformer composed of an induction coil. The high-Tc SQUID is used in order to realize high sensitivity, compact, and low-running cost magnetometer for biomedical applications such as characterization of magnetic nanoparticles. A first-order planar gradiometer with a compensation coil was used as the detection coil to achieve high sensitivity and cancellation factor. We fabricate an electromagnet with primary and small secondary excitation coils to enable a wide range of the excitation magnetic field with a high resolution. To reduce the magnetic field’s drift, we apply a digital feedback program to control the electrical current of the electromagnet. The performance of the developed system is demonstrated by measuring the magnetization curve and AC responses of an iron oxide composite sample. The sensitivity showed by the developed magnetometer reveals its potential for a highly sensitive magnetic property characterization.
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References
Adachi S, Tsukamoto A, Oshikubo Y et al (2011) Fabrication of integrated HTS-SQUID magnetometers having multiturn input coils with different sizes. Phys C Supercond Appl 471:1258–1262. https://doi.org/10.1016/j.physc.2011.05.173
Araujo JFDF, Bruno AC, Louro SRW (2015) Versatile magnetometer assembly for characterizing magnetic properties of nanoparticles. Rev Sci Instrum. https://doi.org/10.1063/1.4931989
Berkov DV, Görnert P, Buske N et al (2000) New method for the determination of the particle magnetic moment distribution in a ferrofluid. J Phys D Appl Phys 33:331–337. https://doi.org/10.1088/0022-3727/33/4/303
Bryant HC, Adolphi NL, Huber DL et al (2011) Magnetic properties of nanoparticles useful for SQUID relaxometry in biomedical applications. J Magn Magn Mater 323:767–774. https://doi.org/10.1016/j.jmmm.2010.10.042
Fagaly RL (2006) Superconducting quantum interference device instruments and applications. Rev Sci Instrum 77:101101. https://doi.org/10.1063/1.2354545
Foner S (1959) Versatile and sensitive vibrating-sample magnetometer. Rev Sci Instrum 30:548. https://doi.org/10.1063/1.1716679
Gleich B, Weizenecker J (2005) Tomographic imaging using the nonlinear response of magnetic particles. Nature 435:1214–1217. https://doi.org/10.1038/nature03808
Jaufenthaler A, Schier P, Middelmann T et al (2020) Quantitative 2D magnetorelaxometry imaging of magnetic nanoparticles using optically pumped magnetometers. Sensors 20:753. https://doi.org/10.3390/s20030753
Ludwig F, Heim E, Mäuselein S et al (2005) Magnetorelaxometry of magnetic nanoparticles with fluxgate magnetometers for the analysis of biological targets. J Magn Magn Mater 293:690–695. https://doi.org/10.1016/j.jmmm.2005.02.045
Pasquarelli A, Del GC, Della PS et al (1996) A SQUID based AC susceptometer for the investigation of large samples. Phys Med Biol 41:2533–2539. https://doi.org/10.1088/0031-9155/41/11/020
Pelizzone M, Treyvaud A (1981) A SQUID susceptometer for fields up to 8.5 tesla. Appl Phys 24:375–379. https://doi.org/10.1007/BF00899737
Petrucha V, Novotny D (2018) Testing and application of an integrated fluxgate sensor DRV425. J Electr Eng 69:418–421. https://doi.org/10.2478/jee-2018-0064
Philo JS, Fairbank WM (1977) High-sensitivity magnetic susceptometer employing superconducting technology. Rev Sci Instrum 48:1529–1536. https://doi.org/10.1063/1.1134952
Saari MM, Sakai K, Kiwa T et al (2012) Development of a compact moving-sample magnetometer using high-Tc superconducting quantum interference device. Jpn J Appl Phys 51:046601. https://doi.org/10.1143/JJAP.51.046601
Saari MM, Sakai K, Kiwa T, Tsukada K (2013) Optimization of the detection technique for a vibrating-sample magnetometer using high-Tc SQUID. IEEE Trans Appl Supercond 23:1600204. https://doi.org/10.1109/TASC.2012.2227919
Saari MM, Ishihara Y, Tsukamoto Y et al (2015) Optimization of an AC/DC High-Tc SQUID magnetometer detection unit for evaluation of magnetic nanoparticles in solution. IEEE Trans Appl Supercond 25:1–4. https://doi.org/10.1109/TASC.2014.2363633
Saari MM, Che Lah NA, Sakai K et al (2018) Harmonics distribution of iron oxide nanoparticles solutions under diamagnetic background. J Magn Magn Mater. https://doi.org/10.1016/j.jmmm.2017.12.054
Sakai K, Saari MM, Kiwa T, Tsukada K (2013) Compact rotating-sample magnetometer for relaxation phenomenon measurement using HTS-SQUID. IEEE Trans Appl Supercond. https://doi.org/10.1109/TASC.2012.2234324
Smith D (1956) Development of a vibrating-coil magnetometer. Rev Sci Instrum 27:261–268. https://doi.org/10.1063/1.1715538
Tanaka S, Akai T, Takemoto M et al (2010) Application of SQUID to magnetic contaminant detection. Phys C Supercond 470:1507–1510. https://doi.org/10.1016/j.physc.2010.05.150
Tsukada K, Kiwa T, Tahara H et al (2009) Highly sensitive measurement of moisture content using HTS-SQUID. IEEE Trans Appl Supercond 19:878–881. https://doi.org/10.1109/TASC.2009.2019659
Tsukamoto A, Adachi S, Oshikubo Y et al (2013) Development of a HTS SQUID module for use with an external pickup coil. Supercond Sci Technol 26:15013. https://doi.org/10.1088/0953-2048/26/1/015013
Acknowledgements
This work is supported by the “Strategic Promotion of Innovative R&D” program funded by the Japan Science and Technology Agency (JST). The high-Tc SQUID was developed and provided by the Superconducting Sensing Technology Research Association (SUSTERA), Japan.
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Saari, M.M., Sakai, K., Kiwa, T. et al. A sensitive magnetometer utilizing high-Tc SQUID for magnetic property characterization. Microsyst Technol 27, 3413–3420 (2021). https://doi.org/10.1007/s00542-020-05198-6
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DOI: https://doi.org/10.1007/s00542-020-05198-6