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Epidermal antenna in palmar arch region for anaemia detection to avoid peripheral perfusion artifact in optical sensor during hemoglobin measurement

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Abstract

The anaemia disease diagnosed with various test such as complete blood count (CBC), ferritin measure, reticulocyte count, peripheral smear and blood gas analyser. The ferritin measure the storage and usage of iron in human body, reticulocyte count assess young red blood cell, and Peripheral smear analyse the cell colour, size, and shape of red blood cell through microscopic image. The blood gas analyser measures methemoglobin (MetHb) and carboxyhaemoglobin. Different test measure haemoglobin, since iron level show normal in blood for the patient with low total body iron. The iron deficiency never show symptom or sign in the human body. In this paper, we propose a new non-invasive method for anaemia measure through epidermal antenna over ulnar region of palm and acquire radiating signal from Haemoglobin protein. The acquired signal from epidermal antenna analysed with Transverse Dyadic Wavelet Transform for haemoglobin protein level in red blood cell. The epidermal antenna signal from ulnar region haemoglobin measurement avoids the peripheral perfusion artifact of optical or image sensor which arise during measurement. The experimental analysis show signal of epidermal antenna measure the haemoglobin more accurately, through regression modelling than existing optical and image based point of care device. Experimental result of haemoglobin measurement from ulnar region has validated with blood gas analyser.

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Authors and Affiliations

  1. Department of ECE, R.M.K. College of Engineering and Technology, Chennai, India

    V. Kannagi

  2. Department of ECE, SSN College of Engineering, Kalavakkam, 603110, India

    A. Jawahar

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  1. V. Kannagi
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  2. A. Jawahar
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Correspondence to V. Kannagi.

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Kannagi, V., Jawahar, A. Epidermal antenna in palmar arch region for anaemia detection to avoid peripheral perfusion artifact in optical sensor during hemoglobin measurement. Microsyst Technol 26, 1427–1435 (2020). https://doi.org/10.1007/s00542-019-04675-x

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  • DOI: https://doi.org/10.1007/s00542-019-04675-x

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