Microsystem Technologies

, Volume 18, Issue 6, pp 823–832 | Cite as

Analytical, numerical and experimental investigations of mixing fluids in microchannel

  • P. K. Sahu
  • A. Golia
  • A. K. SenEmail author
Technical Paper


This work presents theoretical analysis, numerical simulation, fabrication and test of a micromixer chip for mixing fluids in microchannel. A three-dimensional analytical model is developed using a different mathematical approach to study passive laminar mixing phenomena and predict concentration distribution in a microchannel. The analytical model is validated by comparing with experimental and simulation results. The process of mixing fluids in a microchannel is simulated by solving the continuity, momentum and mass diffusion equations. The simulation results are validated and then parametric studies are performed to investigate the effects of channel aspect ratio, Reynolds number and diffusion coefficient on the mixing performance. The micromixer chip is fabricated with patterned SU-8 photoresist as the microchannel layer on a PMMA substrate using a combination of photolithography and micro-milling. Experiments are performed with different mixing fluids and the results were compared with that obtained from the theoretical model and simulation results.


High Aspect Ratio Microfluidic Chip Follow Boundary Condition Active Mixer PMMA Substrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The authors would like to acknowledge the Science and Engineering Research Council (SERC), Department of Science and Technology (DST), India for providing financial support for the project.


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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.Department of Mechanical EngineeringIndian Institute of Technology GuwahatiGuwahatiIndia
  2. 2.Department of Mechanical EngineeringIndian Institute of Technology MadrasChennaiIndia

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