Analytical, numerical and experimental investigations of mixing fluids in microchannel
- 544 Downloads
This work presents theoretical analysis, numerical simulation, fabrication and test of a micromixer chip for mixing fluids in microchannel. A three-dimensional analytical model is developed using a different mathematical approach to study passive laminar mixing phenomena and predict concentration distribution in a microchannel. The analytical model is validated by comparing with experimental and simulation results. The process of mixing fluids in a microchannel is simulated by solving the continuity, momentum and mass diffusion equations. The simulation results are validated and then parametric studies are performed to investigate the effects of channel aspect ratio, Reynolds number and diffusion coefficient on the mixing performance. The micromixer chip is fabricated with patterned SU-8 photoresist as the microchannel layer on a PMMA substrate using a combination of photolithography and micro-milling. Experiments are performed with different mixing fluids and the results were compared with that obtained from the theoretical model and simulation results.
KeywordsHigh Aspect Ratio Microfluidic Chip Follow Boundary Condition Active Mixer PMMA Substrate
The authors would like to acknowledge the Science and Engineering Research Council (SERC), Department of Science and Technology (DST), India for providing financial support for the project.
- Berad DA (2001) Taylor dispersion of a solute in a microfluidic channel. J Appl Phys 89:4467–4469Google Scholar
- Evans J, Liepmann D, Pisano AP (1997) Planar laminar mixer. In: Proceeding of the 10th IEEE international workshop on micro electro mechanical systems (MEMS’97), Nagoya, Japan, pp 96–101Google Scholar
- Kamholz AE, Yager P (2002) Molecular diffusive scaling laws in pressure-driven microfluidic channels: deviation from onedimensional Einstein approximations. Sensor Actuat B Chem 82:117–121Google Scholar
- Miyake R, Lammerink TSJ, Elwenspoek M, Fluitman JHJ (1993) Micro mixer with fast diffusion. In: Proceedings of the 6th IEEE international workshop on micro electro mechanical systems (MEMS’93). Fort Lauderdale, Florida, pp 248–253Google Scholar