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Interfacial configurations and mixing performances of fluids in staggered curved-channel micromixers

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Abstract

We present a parallel laminar micromixer with staggered curved channels for homogeneously mixing two fluids by Dean vortex. The secondary flows are produced in curved rectangular channels by the centrifugal forces; the diffusion distance of two fluids is reduced due to the staggered structures of the flow channels. The mixing strength is increased when one stream is injected into the other. Confocal microscopy and pH indicator have been used to study the mixing. Computational fluid dynamics simulations are utilized to examine the interfacial configurations and the mixing behaviors inside the channels. The interface of the two fluids is heavily distorted and increases the interfacial area because of the unique structures. The mixing index of the staggered curved-channel mixer with tapered channels is higher than those of the other curved-channel mixers. The effects of various Reynolds numbers and channel configurations on mixing performances are investigated in terms of the experimental mixing indices and the computational interfacial patterns. The comparison between the experimental data and numerical results shows a very similar trend.

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References

  • Ansari MA, Kim KY, Anwar K, Kim SM (2010) A novel passive micromixer based on unbalanced splits and collisions of fluid streams. J Micromech Microeng 20:055007

    Article  Google Scholar 

  • Bessoth FG, deMello AJ, Manz A (1999) Microstructure for efficient continuous flow mixing. Anal Commun 36:213–215

    Article  Google Scholar 

  • Bohm S, Greiner K, Schlautmann S, de Vries S, van den Berg A (2001) A rapid vortex micromixer for studying high-speed chemical reactions. In: Proceedings of the 5th international conference on micro total analysis systems, micro-TAS 2001:25–27

  • Caldin EF (1964) Fast reactions in solution. Wiley, New York

    Google Scholar 

  • Chaktranond C, Fukagata K, Kasagi N (2008) Performance assessment and improvement of a split-and-recombine micromixer for immunomagnetic cell sorting. J Fluid Sci Technol 3:1008–1019

    Article  Google Scholar 

  • Chen JJ, Chen CH, Shie SR (2011a) Optimal designs of staggered Dean vortex micromixers. Int J Mol Sci 12:3500–3524

    Article  Google Scholar 

  • Chen JJ, Lai YR, Tsai RT, Lin JD, Wu CY (2011b) Crosswise ridge micromixers with split and recombination helical flows. Chem Eng Sci 66:2164–2176

    Article  Google Scholar 

  • Ghia KN, Sokhey JS (1977) Laminar incompressible viscous flow in curved ducts of regular cross section. J Fluids Eng 99:640–648

    Article  Google Scholar 

  • Hessel V, Lowe H, Schönfeld F (2005) Micromixers-a review on passive and active mixing principles. Chem Eng Sci 60:2479–2501

    Article  Google Scholar 

  • Jeong GS, Chung S, Kim CB, Lee SH (2010) Applications of micromixing technology. Analyst 135:460–473

    Article  Google Scholar 

  • Jiang F, Dress KS, Hardt S, Kupper M, Schönfeld F (2004) Helical flows and chaotic mixing in curved micro channels. AIChE 50:2297–2305

    Article  Google Scholar 

  • Koch M, Chatelain D, Evans AGR, Brunnschweiler A (1998) Two simple micromixers based on silicon. J Micromech Microeng 8:123–126

    Article  Google Scholar 

  • Kockmann N, Kiefer T, Engler M, Woias P (2006) Convective mixing and chemical reactions in microchannels with high flow rates. Sensor Actuat B Chem 117:495–508

    Article  Google Scholar 

  • McQuain MK, Seale K, Peek J, Fisher TS, Levy S, Stremler MA, Haseltona FR (2004) Chaotic mixer improves microarray hybridization. Anal Biochem 325:215–226

    Article  Google Scholar 

  • Melin J, Gimenéz G, Roxhed N, van der Wijngaart W, Stemme G (2004) A fast passive and planar liquid sample micromixer. Lab Chip 4:214–219

    Article  Google Scholar 

  • Mouza AA, Patsa CM, Schönfeld F (2008) Mixing performance of a chaotic micro-mixer. Chem Eng Res Des 86:1128–1134

    Article  Google Scholar 

  • Nguyen NT (2011) Micromixers: fundamentals, design and fabrication. William Andrew Inc, New York

    Google Scholar 

  • Nguyen NT, Wu Z (2005) Micromixers-a review. J Micromech Microeng 15:R1–R16

    Article  Google Scholar 

  • Nguyen TNT, Kim MC, Park JS, Lee NE (2008) An effective passive microfluidic mixer utilizing chaotic advection. Sensor Actuat B Chem 132:172–181

    Article  Google Scholar 

  • Schönfeld F, Hessel V, Hofmann C (2004) An optimised split-and-recombine micro-mixer with uniform ‘chaotic’ mixing. Lab Chip 4:65–69

    Article  Google Scholar 

  • Sewall EA, Tafti DK, Graham AB, Thole KA (2006) Experimental validation of large eddy simulations of flow and heat transfer in a stationary ribbed duct. Int J Heat Fluid Flow 27:243–258

    Article  Google Scholar 

  • Stroock AD, Dertinger SKW, Ajdari A, Mezić I, Stone HA, Whitesides GM (2002) Chaotic mixer for microchannels. Science 295:647–651

    Article  Google Scholar 

  • Sudarsan AP, Ugaz VM (2006) Multivortex micromixing. PNAS 103:7228–7233

    Article  Google Scholar 

  • Sui Y, Teo CJ, Lee PS, Chew YT, Shu C (2010) Fluid flow and heat transfer in wavy microchannels. Int J Heat Mass Transf 53:2760–2772

    Article  MATH  Google Scholar 

  • Xie C, Bostaph J, Pavio J (2004) Development of a 2 W direct methanol fuel cell power source. J Power Sources 136:55–65

    Article  Google Scholar 

  • Yamaguchi Y, Takagi F, Yamashita K, Nakamura H, Maeda H, Sotowa K, Kusakabe K, Yamasaki Y, Morooka S (2004) 3-D simulation and visualization of laminar flow in a microchannel with hair-pin curves. AIChE 50:1530–1535

    Article  Google Scholar 

  • Yang JT, Huang KJ, Lin YC (2005) Geometric effects on fluid mixing in passive grooved micromixers. Lab Chip 5:1140–1147

    Article  Google Scholar 

Download references

Acknowledgments

The authors would like to thank the National Science Council of the Republic of China, Taiwan, for financially supporting this research under Contract No. NSC100-2221-E-020-024-. Daryl Switak is appreciated for his editorial assistance.

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Correspondence to Jyh Jian Chen.

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Chen, J.J., Shie, Y.S. Interfacial configurations and mixing performances of fluids in staggered curved-channel micromixers. Microsyst Technol 18, 1823–1833 (2012). https://doi.org/10.1007/s00542-012-1489-x

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  • DOI: https://doi.org/10.1007/s00542-012-1489-x

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