Skip to main content
Log in

Soft lithography replication based on PDMS partial curing

  • Technical Paper
  • Published:
Microsystem Technologies Aims and scope Submit manuscript

Abstract

In this paper, a partial curing technique is presented. Its aim is to enable the soft lithography replication process for the case requiring usage of PDMS mold. Through controlling the curing time during molding step, the liquid PDMS prepolymer in original status, which will later constitute the device substrate, can be partially polymerized as well as solidified. As a result, not only can the structural pattern in the mold be successfully transferred into the device layer, but also the spontaneous adhesive interaction between these two PDMS parts happening during curing can be effectively limited within very low level, thus largely facilitating the demoulding process. Based on this process, several devices have been successfully developed and high fidelity pattern transfer capability has also been demonstrated. Comparing with the most commonly used treatments such as silanization, the presented method demonstrates easier operation and better user-friendly interface advantages.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9

Similar content being viewed by others

References

  • Aarash YNS, Cristina M (2010) A vapor-assisted method for adhering polydimethylsiloxane and glass. Lab Chip 10:250–253

    Article  Google Scholar 

  • Abdelgawad M, Watson MWL, Young EWK, Mudrik JM, Ungrin MD, Wheeler AR (2008) Soft lithography: masters on demand. Lab Chip 8:1379–1385

    Article  Google Scholar 

  • Armani AM, Srinivasan A, Vahala KJ (2007) Soft lithography fabrication of high Q polymer microcavity arrays. Nano Lett 7:1823–1826

    Article  Google Scholar 

  • Bliss CL, McMullin JN, Backhouse CJ (2007) Rapid fabrication of a microfluidic device with integrated optical waveguides for DNA fragment analysis. Lab Chip 7:1280–1287

    Article  Google Scholar 

  • Duffy DC, McDonald JC, Schueller OJA, Whitesides GM (1998) Rapid prototyping of microfluidic systems in poly (dimethylsiloxane). Analyt Chem 70:4974–4984

    Article  Google Scholar 

  • Ferguson GS, Chaudhury MK, Biebuyck HA, Whitesides GM (1993) Monolayers on disordered substrates: self-assembly of alkyltrichlorosilanes on surface-modified polyethylene and poly (dimethylsiloxane). Macromolecules 26:5870–5875

    Article  Google Scholar 

  • Futai N, Gu W, Takayama S (2004) Rapid prototyping of microstructures with bell-shaped cross-sections and its application to deformation-based microfluidic valves. Adv Mater 16:1320–1323

    Article  Google Scholar 

  • Gitlin L, Schulze P, Belder D (2009) Rapid replication of master structures by double casting with PDMS. Lab Chip 9:3000–3002

    Article  Google Scholar 

  • Hoffman JM, Shao J, Hsu CH, Folch A (2004) Elastomeric molds with tunable microtopography. Adv Mater 16:2201–2206

    Article  Google Scholar 

  • Huang Y, Paloczi GT, KS PoonJ, Yariv A (2004) Bottom-up soft-lithographic fabrication of three dimensional multilayer polymer integrated optical microdevices. Appl Phys Lett 85:3005–3007

    Article  Google Scholar 

  • Hung LH, Lin R, Lee AP (2008) Rapid microfabrication of solvent-resistant biocompatible microfluidic devices. Lab Chip 8:983–987

    Article  Google Scholar 

  • Kim DS, Lee SH, Ahn CH, Lee JY, Kwon TH (2006) Disposable integrated microfluidic biochip for blood typing by plastic microinjection moulding. Lab Chip 6:794–802

    Article  Google Scholar 

  • McDonald JC, Duffy DC, Anderson JR, Chiu DT, Wu H, Schueller OJA, Whitesides GM (2000) Fabrication of microfluidic systems in poly (dimethylsiloxane). Electrophoresis 21:27–40

    Article  Google Scholar 

  • Monat C, Domachuk P, Eggleton BJ (2007) Integrated optofluidics: a new river of light. Nat Photonics 1:106–114

    Article  Google Scholar 

  • Pal P, Sato K (2009) Complex three-dimensional structures in Si{1 0 0} using wet bulk micromachining. J. Micromech. Microeng.19: 105008-1-9

    Google Scholar 

  • Psaltis D, Quake SR, Yang C (2006) Developing optofluidic technology through the fusion of microfluidics and optics. Nature 442:381–386

    Article  Google Scholar 

  • Sia SK, Whitesides GM (2003) Microfluidic devices fabricated in poly (dimethylsiloxane) for biological studies. Electrophoresis 24:3563–3576

    Article  Google Scholar 

  • Unger MA, Chou HP, Thorsen T, Scherer A, Quake SR (2000) Monolithic microfabricated valves and pumps by multilayer soft lithography. Science 288:113–116

    Article  Google Scholar 

  • Urbanski JP, Thies W, Rhodes C, Amarasinghe S, Thorsen T (2006) Digital microfluidics using soft lithography. Lab Chip 6:96–104

    Article  Google Scholar 

  • Weston DF, Smekal T, Rhine DB, Blackwell J (2001) Fabrication of microfluidic devices in silicon and plastic using plasma etching. J Vac Sci Technol B 19:2846–2851

    Article  Google Scholar 

  • Xia Y, Whitesides GM (1998) Soft Lithography. Annu Rev Mater Sci 28:153–184

    Article  Google Scholar 

  • Yu HB, Zhou GY, Chau FS, Lee FW (2008a) Optofluidic variable aperture. Opt Lett 33:548–550

    Article  Google Scholar 

  • Yu HB, Zhou GY, Chau FS, Lee FW, Wang SH (2008b) A tunable Shack–Hartmann wavefront sensor based on a liquid-filled microlens array. J Micromech Microeng 18:105017

    Article  Google Scholar 

  • Yu HB, Zhou GY, Chau FS, Lee FW (2009a) Phase-transmission-grating-based compact optofluidic refractometer. Opt Lett 34:1753–1755

    Article  Google Scholar 

  • Yu HB, Zhou GY, Chau FS, Lee FW, Wang SH, Leung HM (2009b) A liquid-filled tunable double-focus microlens. Opt Express 17:4782–4790

    Article  Google Scholar 

  • Yu HB, Zhou GY, Chau FS, Wang SH, Lee FW (2009c) Novel polydimethylsiloxane (PDMS) based microchannel fabrication method for lab-on-a-chip application. Sensor Actuat B-chem 137:754–761

    Article  Google Scholar 

  • Zhang DY, Justis N, Lo YH (2009) Integrated fluidic adaptive zoom lens. Opt Lett 29:2855–2857

    Article  Google Scholar 

  • Zhou GY, Leung HM, Yu HB, Kumar AS, Chau FS (2009) Liquid tunable diffractive/refractive hybrid lens. Opt Lett 34:2793–2795

    Article  Google Scholar 

  • Zhu L, Huang Y, Yariv A (2005) Integrated microfluidic variable optical attenuator. Opt Express 13:9916–9921

    Article  Google Scholar 

Download references

Acknowledgments

Financial support by the National Research Foundation (NRF), Singapore under Award No. NRF-CRP 2-2007-04 is gratefully acknowledged.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hongbin Yu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yu, H., Zhou, G., Chau, F.S. et al. Soft lithography replication based on PDMS partial curing. Microsyst Technol 17, 443–449 (2011). https://doi.org/10.1007/s00542-011-1273-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00542-011-1273-3

Keywords

Navigation