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A UML-based object-oriented approach for design and simulation of a drug delivery system

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Abstract

Given complexity of the design and manufacturing processes of microelectromechanical system (MEMS) products, we present a unified modeling language (UML) based design approach for multi-domain products or systems like MEMS to designing and evaluating possible solutions at the early design stage to shorten their development time. Specifically, the proposed approach is used to model and analyze a novel drug delivery system combining MEMS devices and integrated circuit (IC) units. This drug delivery system aims to be used for safer and more effective therapy of the diabetics. Two design models about the whole drug delivery system and its micropump subsystem are established using UML diagrams; in particular a composition diagram with components and ports describes the topology of the system. Through design and simulation on the micropump subsystem, it is found that the variations of geometrical dimension and excitation voltage affect the characterization of the micropump. The simulation results demonstrate and validate the proposed approach, and can be used as a significant reference for the designer to design the optimal micropump.

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Acknowledgments

The authors gratefully acknowledge the financial support of this research by National Natural Science Foundation of China (Grant No. 50575145). No approval or endorsement by US National Institute of Standards and Technology is intended or implied.

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Authors and Affiliations

  1. School of Mechanical Engineering, Shanghai JiaoTong University, Dongchuan Road 800, 200240, Shanghai, China

    Qifeng Cui, Xuan F. Zha & Chengliang Liu

  2. Extension Systems International, National Institute of Standards and Technology and University of Maryland at College Park, Gaithersburg, MD, 20899, USA

    Xuan F. Zha

  3. Department of Mechanical Engineering/Centre for Design Technology, National University of Singapore, Singapore, 638075, Singapore

    Wen F. Lu

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  1. Qifeng Cui
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  2. Xuan F. Zha
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  3. Chengliang Liu
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  4. Wen F. Lu
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Correspondence to Chengliang Liu.

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Cui, Q., Zha, X.F., Liu, C. et al. A UML-based object-oriented approach for design and simulation of a drug delivery system. Microsyst Technol 14, 855–869 (2008). https://doi.org/10.1007/s00542-008-0616-1

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  • DOI: https://doi.org/10.1007/s00542-008-0616-1

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