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The Effect of sevoflurane on rat liver mitochondrial respiration

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Abstract

The effect of sevoflurane on rat liver mitochondrial respiration has been investigated with a Clark type oxygen electrode at 25°C, pH 7.4. The higher susceptibility of NADH-linked substrate (glutamate) oxidation (with respect to succinate oxidation) to the damages by sevoflurane has been confirmed.

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Author notes

  1. Hideo Yokoyama

    Present address: Department of Anesthesiology, Tohyoko General Hospital, St Marianna University, Shcool of Medicine, Kosugi 3-435, Nakahara-ku, 211, Kawasaki, Japan

Authors and Affiliations

  1. Department of Anesthesiology, Tokyo Medical College, Tokyo, Japan

    Junko Nonaka & Reiko Matsuo

  2. Department of Anesthesiology, Tohyoko General Hospital, St Marianna University, Shcool of Medicine, Kosugi 3-435, Nakahara-ku, 211, Kawasaki, Japan

    Noriyasu Kubota, Toshiyuki Shibata & Keizo Takahashi

Authors
  1. Hideo Yokoyama
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  2. Noriyasu Kubota
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  3. Toshiyuki Shibata
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  4. Junko Nonaka
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  5. Reiko Matsuo
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  6. Keizo Takahashi
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Yokoyama, H., Kubota, N., Shibata, T. et al. The Effect of sevoflurane on rat liver mitochondrial respiration. J Anesth 7, 257–259 (1993). https://doi.org/10.1007/s0054030070257

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  • DOI: https://doi.org/10.1007/s0054030070257

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