Systemic administration of procaine suppresses the somato-sympathetic reflex discharges in anesthetized cats
- 22 Downloads
Somato-sympathetic reflex discharges (SSRDs) which were induced from the lumbar sympathetic truck elicited by train pulse stimulation of femoral nerves in anesthetized cats were examined during and after intravenous infusion of 1 mg·kg−1·min−1 of procaine. The infusion demonstrated that amplitudes were suppressed with prolonged latencies and/or their tendencies in A- and C-reflex potentials of SSRDs. Heart rate and blood pressure decreased slightly, and the decreases correlated with time courses of suppressed SSRDs. These results suggest that the systemic procaine infusion may be a reliable method to alleviate somato-sympathetic reflexes under such conditions as extreme stimulation of somatic afferent nerves observed in surgical procedures.
Key wordssystemic procaine infusion somato-sympathetic reflex discharge A-reflex potential C-reflex potential
Unable to display preview. Download preview PDF.
- 7.Ogawa S, Kanayama T, Yazaki S, et al: A study on mechanisms of pain relief following sympathetic ganglion block: reflex sympathetic potential elicited by femoral vein stimulation. Masui (Jpn J Anesthesiol) 31:927–932, 1982Google Scholar
- 8.Sato A, Tsushima N, Fujimori B: Reflex potentials of lumbar sympathetic trunk with sciatic nerve stimulation in cats. Jap J Physiol 17:294–307, 1967Google Scholar
- 9.Sato A, Sato N, Izawa T, et al: Further observations of reflex potentials in lumbar sympathetic trunk in cats. Jap J Physiol 17:294–307, 1967Google Scholar
- 10.Sato A, Schmidt RF: Somatosympathetic reflex: afferent fibers, central pathways discharge characterristics. Physiol Rev 53:916–947Google Scholar
- 13.Sato A, Adachi T, Sato N: The effect of analgesics on somatically induced sympathetic reflexes in anesthetized animals. Pain Clinic 10:605–612, 1989Google Scholar
- 14.Kato J, Ogawa S, Suzuki H: Effects of diazepam on somato-sympathetic reflex discharges in anesthetized cats. Pain Research 6:165–168, 1991Google Scholar